RECRUITING

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research study is to determine how training to step with a metronome on both a treadmill, as well as overground, will influence the way that people with Parkinson disease walk. Using metronomes is commonly used in clinics, but the investigators will be using a combination of slow and fast frequencies to alter the way that people walk. The use of a slower frequency metronome on the treadmill is intended to help participants take larger steps. The use of a faster frequency metronome while walking overground is intended to help participants take faster steps.This will take place over 12 training sessions. Each session will be about an hour. It will include some walking tests and pictures of the brain (using MRI) before and after training.

Official Title

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Quick Facts

Study Start:2023-08-16
Study Completion:2026-05-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05864157

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * idiopathic Parkinson's disease (Hoehn and Yahr Stage 2-3)
  2. * self-report the ability to walk uninterrupted for 10 minutes both overground and on a treadmill without therapist assistance
  3. * comfortable gait speed \> 0.4 m/s and \< 1.2 m/s
  4. * normal (or corrected to normal \[i.e., hearing aid\]) hearing
  5. * deficits in gait continuity (e.g., shuffling, shortened strides, freezing, festination, bradykinesia, etc) based on observational gait analysis
  6. * Movement Disorders Society - Unified Parkinson Disease Rating Scale (MDS-UPDRS-III) item 10 ≥1 and \<3
  7. * be on stable doses of orally-administered levodopa
  8. * age 50-80 years old
  1. * contraindications to MRI (e.g., metal implants, claustrophobia, etc)
  2. * cognitive deficits (Montreal Cognitive Assessment \[MoCA\] \< 26)
  3. * concurrent Physical Therapy
  4. * have undergone deep brain stimulation surgery
  5. * cannot walk without therapist assistance
  6. * uncontrolled cardiorespiratory/metabolic disease, or other neurological disorders or orthopedic injury that may affect gait.

Contacts and Locations

Study Contact

Mike Lewek, PT, PhD
CONTACT
919-966-4041
mlewek@med.unc.edu

Principal Investigator

Mike Lewek, PT, PhD
PRINCIPAL_INVESTIGATOR
Associate Professor

Study Locations (Sites)

University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599
United States

Collaborators and Investigators

Sponsor: University of North Carolina, Chapel Hill

  • Mike Lewek, PT, PhD, PRINCIPAL_INVESTIGATOR, Associate Professor

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-16
Study Completion Date2026-05-03

Study Record Updates

Study Start Date2023-08-16
Study Completion Date2026-05-03

Terms related to this study

Keywords Provided by Researchers

  • Gait
  • Rehabilitation

Additional Relevant MeSH Terms

  • Parkinson Disease