RECRUITING

Written Exposure Therapy for Suicide Prevention

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on inpatient psychiatric units to reduce the risk of post-discharge SITBs. To address this gap, the investigator's research group developed Written Exposure Therapy for Suicide Prevention (WET-SP), a brief, scalable, suicide-specific psychotherapy based on the written disclosure paradigm. Written disclosure, in which an individual writes about a personally stressful experience and the related thoughts and feelings, yields improvements across physical and psychiatric domains. Pilot data suggest that written exposure also yields reductions in SITBs. Yet, no study has adapted the written exposure paradigm specifically to target the amelioration of distress associated with suicidal crises and examined whether implementing WET-SP reduces the risk of subsequent SITBs and suicide-related hospitalizations. The primary objective of this randomized controlled trial (RCT) is to evaluate the efficacy of WET-SP, in reducing the incidence and severity of SITBs in active duty military service members following a psychiatric hospitalization due to suicidal ideation, suicide plans, or a suicide attempt. Secondary objectives are to evaluate a potential mechanism of change (i.e., decreases in thwarted belongingness \[cf. social disconnectedness\]) and moderator of outcomes (i.e., arc of narrative \[cf. linguistical parameters of the written narratives generated during treatment\]). Participants randomized to WET-SP + TAU will receive five sessions of WET-SP delivered by the study team during their psychiatric hospitalization plus treatment-as-usual (TAU). Participants randomized to TAU will receive daily contact and patient-centered care delivered by the acute psychiatric inpatient unit provider team (e.g., psychiatrists, therapists, case managers). TAU includes psychiatric assessment, initial stabilization, nurse case management, medication management, treatment of medical comorbidities, group and individual therapy, and discharge planning. Outcome assessments will be administered at pretreatment, posttreatment, and 10-, 20-, and 30-week follow-ups.

Official Title

Written Exposure Therapy for Suicide Prevention (WET-SP)

Quick Facts

Study Start:2024-08-20
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05878795

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Current active duty military service member
  2. * Admitted to Carl R. Darnall Army Medical Center (CRDAMC) for suicidal thoughts, a suicide plan, or a suicide attempt
  3. * Elevated levels of suicidal ideation severity in the past two weeks, as indicated by a score \>3 on the Depressive Symptom Index-Suicidality Subscale (DSI-SS; Joiner et al., 2002; Stanley et al., 2021)
  4. * Ability to read, write, and speak English
  1. * Active psychosis as the priority of care for hospitalization
  2. * Moderate or greater cognitive impairment (as determined by the inability to comprehend the baseline screening questionnaires)
  3. * Unable to provide informed consent

Contacts and Locations

Study Contact

Brian P Marx, PhD
CONTACT
857-364-6071
bpmarx@bu.edu
Denise M Sloan, PhD
CONTACT
857-364-6333
dsloan@bu.edu

Principal Investigator

Brian P Marx, PhD
PRINCIPAL_INVESTIGATOR
Dept of Psychiatry, Chobanian & Avedisian BU School of Medicine and VA Boston Healthcare System

Study Locations (Sites)

University of Texas Health Center San Antonio
San Antonio, Texas, 78229
United States

Collaborators and Investigators

Sponsor: Boston University

  • Brian P Marx, PhD, PRINCIPAL_INVESTIGATOR, Dept of Psychiatry, Chobanian & Avedisian BU School of Medicine and VA Boston Healthcare System

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-20
Study Completion Date2025-06

Study Record Updates

Study Start Date2024-08-20
Study Completion Date2025-06

Terms related to this study

Keywords Provided by Researchers

  • Self-injurious thoughts and behaviors (SITBs)
  • Written Exposure Therapy for Suicide Prevention (WET-SP)
  • Military service members
  • Treatment as usual (TAU)

Additional Relevant MeSH Terms

  • Suicide, Attempted
  • Suicide Threat