Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study

Description

Study to enroll up to 90 individuals, those with an alcohol use disorder (AUD) (up to n=60) and non-dependent healthy volunteers (HV) (up to n=30). PET/CT imaging will be used to evaluate brain and whole-body inflammation using the investigational radiotracer \[18F\]NOS. All participants will have one \[18F\]NOS positron emission tomography/ computed tomography (PET/CT) scan performed.

Conditions

Alcohol Use Disorder

Study Overview

Study Details

Study overview

Study to enroll up to 90 individuals, those with an alcohol use disorder (AUD) (up to n=60) and non-dependent healthy volunteers (HV) (up to n=30). PET/CT imaging will be used to evaluate brain and whole-body inflammation using the investigational radiotracer \[18F\]NOS. All participants will have one \[18F\]NOS positron emission tomography/ computed tomography (PET/CT) scan performed.

Imaging Inflammation in Individuals With Alcohol Use Disorder: an [18F]NOS Study

Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study

Condition
Alcohol Use Disorder
Intervention / Treatment

-

Contacts and Locations

Philadelphia

University of Pennsylvania, Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to 65 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    University of Pennsylvania,

    Jacob Dubroff, MD, PhD, PRINCIPAL_INVESTIGATOR, Perelman School of Medicine, Dept. of Radiology

    Study Record Dates

    2027-03-15