RECRUITING

A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to find out whether the fat ALT flap procedure is a safe and practical option for reducing neck morbidity in HNSCC patients following cancer treatment of the neck. Neck morbidity after radiation therapy and surgery includes difficulty swallowing, neck or shoulder pain, stiffness, swelling, or changes to the appearance of the treated area. In addition, the researchers will find out whether the study procedure is effective at reducing neck morbidity and improving quality of life after cancer treatment. The researchers will measure quality of life by having participants answer questionnaires.

Official Title

The Safety of a Buried, Free Fat Flap to Reduce Neck Morbidity Following Cancer Treatment: A Pilot Study

Quick Facts

Study Start:2023-05-16
Study Completion:2026-05-16
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05889091

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients 18 years or older
  2. * Diagnosed with HNSCC (e.g., oropharyngeal, hypo/laryngeal SCC)
  3. * Primary treatment is with radiotherapy with or without chemotherapy
  4. * Salvage neck dissection is subsequently indicated for persistent or recurrent, nonmucosal disease in cervical lymph nodes
  5. * At the time of salvage neck dissection additional flap coverage is indicated to improve carotid coverage or replace missing skin
  1. * Patients with primary site mucosal recurrence in addition to neck disease

Contacts and Locations

Study Contact

Evan Matros, MD
CONTACT
646-608-8044
matrose@mskcc.org
Jennifer Cracchiolo, MD
CONTACT
212-639-8420

Principal Investigator

Evan Matros, MD
PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065
United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

  • Evan Matros, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-05-16
Study Completion Date2026-05-16

Study Record Updates

Study Start Date2023-05-16
Study Completion Date2026-05-16

Terms related to this study

Keywords Provided by Researchers

  • Free fat flap
  • Reconstruction
  • Quality of life
  • 23-102

Additional Relevant MeSH Terms

  • Head and Neck Squamous Cell Carcinoma