Exercise-Induced Gut Permeability in Normal-weight Obesity

Description

Exercise acutely increases gut permeability and inflammation, even in healthy populations. However, whether this response differs in groups at-risk for CVD that present with low-grade inflammation (e.g., normal-weight obesity) has yet to be examined. The investigators aim to measure serum indicators of gut permeability in those with normal-weight obesity pre- and post-short, intense exercise and sustained, moderate exercise

Conditions

Normal-weight Obesity, Obesity

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Study Overview

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Study Details

Study overview

Exercise acutely increases gut permeability and inflammation, even in healthy populations. However, whether this response differs in groups at-risk for CVD that present with low-grade inflammation (e.g., normal-weight obesity) has yet to be examined. The investigators aim to measure serum indicators of gut permeability in those with normal-weight obesity pre- and post-short, intense exercise and sustained, moderate exercise

Indicators of Gut Permeability in Normal-weight Obesity in Response to Brief, Maximal and Sustained, Submaximal Exercise

Exercise-Induced Gut Permeability in Normal-weight Obesity

Condition
Normal-weight Obesity
Intervention / Treatment

-

Contacts and Locations

Stillwater

208 Nancy Randolph Davis, Oklahoma State University, Stillwater, Oklahoma, United States, 74078

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Presence of pacemaker
  • * Pregnant
  • * Postmenopausal status
  • * History of chronically using of tobacco products, illicit drugs, anti-inflammatory drugs (e.g., NSAIDs), lipid lowering drugs
  • * Recent use of antibiotics (\< 6 weeks) and NSAIDs (\< 3 days)
  • * Established cardiometabolic disease (e.g., cardiovascular disease, type 2 diabetes) diseases inflammatory in nature (e.g., rheumatoid arthritis, inflammatory bowel disease), and/or diagnosed irritable bowel syndrome.

Ages Eligible for Study

18 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Oklahoma State University,

Study Record Dates

2023-08-01