RECRUITING

Exercise-Induced Gut Permeability in Normal-weight Obesity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Exercise acutely increases gut permeability and inflammation, even in healthy populations. However, whether this response differs in groups at-risk for CVD that present with low-grade inflammation (e.g., normal-weight obesity) has yet to be examined. The investigators aim to measure serum indicators of gut permeability in those with normal-weight obesity pre- and post-short, intense exercise and sustained, moderate exercise

Official Title

Indicators of Gut Permeability in Normal-weight Obesity in Response to Brief, Maximal and Sustained, Submaximal Exercise

Quick Facts

Study Start:2023-01-10
Study Completion:2023-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05889767

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Presence of pacemaker
  2. * Pregnant
  3. * Postmenopausal status
  4. * History of chronically using of tobacco products, illicit drugs, anti-inflammatory drugs (e.g., NSAIDs), lipid lowering drugs
  5. * Recent use of antibiotics (\< 6 weeks) and NSAIDs (\< 3 days)
  6. * Established cardiometabolic disease (e.g., cardiovascular disease, type 2 diabetes) diseases inflammatory in nature (e.g., rheumatoid arthritis, inflammatory bowel disease), and/or diagnosed irritable bowel syndrome.

Contacts and Locations

Study Contact

Bryant H Keirns, MS
CONTACT
3166891711
bryant.keirns@okstate.edu
Sam R Emerson, PhD
CONTACT
405-744-2303
sam.emerson@okstate.edu

Study Locations (Sites)

208 Nancy Randolph Davis, Oklahoma State University
Stillwater, Oklahoma, 74078
United States

Collaborators and Investigators

Sponsor: Oklahoma State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-10
Study Completion Date2023-08-01

Study Record Updates

Study Start Date2023-01-10
Study Completion Date2023-08-01

Terms related to this study

Additional Relevant MeSH Terms

  • Normal-weight Obesity
  • Obesity