Yoga for Treatment of Overactive Bladder in Pediatric Patients

Description

The goal of this pilot study is to assess the impact of yoga as a treatment modality in pediatric patients age 8-18 diagnosed with idiopathic overactive bladder as measured by validated questionnaires and urinary biomarkers. The main question it aims to answer is: Does yoga help improve overactive bladder symptoms in this patient population? Participants will take part in a weekly yoga session for a total of 6 weeks with validated questionnaires and urinary samples for biomarkers to be completed at the beginning, middle and end of the study. This study will follow a cross-over study design and patients will receive standard of care while not in the active treatment arm.

Conditions

Overactive Bladder, Overactive Bladder Syndrome, Overactive Detrusor

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Study Details

Study overview

The goal of this pilot study is to assess the impact of yoga as a treatment modality in pediatric patients age 8-18 diagnosed with idiopathic overactive bladder as measured by validated questionnaires and urinary biomarkers. The main question it aims to answer is: Does yoga help improve overactive bladder symptoms in this patient population? Participants will take part in a weekly yoga session for a total of 6 weeks with validated questionnaires and urinary samples for biomarkers to be completed at the beginning, middle and end of the study. This study will follow a cross-over study design and patients will receive standard of care while not in the active treatment arm.

Yoga for Treatment of Overactive Bladder in Pediatric Patients

Yoga for Treatment of Overactive Bladder in Pediatric Patients

Condition
Overactive Bladder
Intervention / Treatment

-

Contacts and Locations

Durham

Duke University Hospital, Durham, North Carolina, United States, 27701

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 8-18 years of age
  • * History of non-neurogenic overactive bladder or detrusor overactivity and/or urinary incontinence (ICD 10 codes respectively - N32.81, N39.498)
  • * Obtained legally effective informed consent and Health Insurance Portability and Accountability Act (HIPPA) authorization from the participant or the participant's parent/legal guardian
  • * Minor participant is willing and able to provide assent (as applicable)
  • * Vancouver Dysfunctional Elimination Syndrome\[15\] score of ≥11 and a positive modified bother score within 30 days of consent
  • * Known or apparent untreated anatomical abnormality of lower urinary tract (i.e. untreated ureterocele)
  • * Known neurogenic bladder (e.g., spina bifida, history of spinal cord injury, tethered cord)
  • * Nerve damage that may impact pelvic floor function
  • * History of chemodenervation of the bladder (e.g., via intravesical instillation or intradetrusor injection of botulinum toxin)
  • * Active, untreated UTI at the time of enrollment (UTI undergoing active treatment is allowable)
  • * Current or previous pregnancy at screening or planned pregnancy during the duration of the study, for females of childbearing potential
  • * Any condition that, in the judgment of the investigator or treating clinician, precludes participation because it could affect participant safety

Ages Eligible for Study

8 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Duke University,

Study Record Dates

2025-09