Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Description

This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors.

Conditions

Breast Cancer, Cognitive Impairments

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Study Overview

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Study Details

Study overview

This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors.

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors: A Multi-Center Randomized Double-Blinded Controlled Trial

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Condition
Breast Cancer
Intervention / Treatment

-

Contacts and Locations

Anchorage

Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States, 98508

Anchorage

Anchorage Radiation Therapy Center, Anchorage, Alaska, United States, 99504

Anchorage

Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States, 99508

Anchorage

Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States, 99508

Anchorage

Alaska Women's Cancer Care, Anchorage, Alaska, United States, 99508

Anchorage

Katmai Oncology Group, Anchorage, Alaska, United States, 99508

Anchorage

Providence Alaska Medical Center, Anchorage, Alaska, United States, 99508

Fairbanks

Fairbanks Memorial Hospital, Fairbanks, Alaska, United States, 99701

Gilbert

Arizona Center for Cancer Care - Gilbert, Gilbert, Arizona, United States, 85297

Goodyear

CTCA at Western Regional Medical Center, Goodyear, Arizona, United States, 85338

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * The participant must provide study-specific informed consent prior to any study specific procedures and authorization permitting release of personal health information.
  • * The participant must have a first time diagnosis of non-metastatic breast cancer which is Stage I-III.
  • * The participant must have a score of less than 12 on the PROMIS Adult v2.0 - Cognitive Function 4a.
  • * Participants with greater than or equal to 6 months to 5 years post-treatment (completion of initial surgery +/- adjuvant chemotherapy/radiation therapy) except may still be taking endocrine therapy or HER2-directed adjuvant therapy.
  • * The participant must be able to understand, speak, read, and write in English or Spanish.
  • * Scoring less than or equal to 3 on the 6-item cognitive screen.
  • * Patient Health Questionnaire-2 item (PHQ-2) score of greater than or equal to 3.
  • * Definitive clinical or radiologic evidence of metastatic disease.
  • * Prior history of past or current other cancer, except for non-melanoma skin cancer or in situ cervical cancer within the past 5 years.
  • * Previous exposure to chemotherapy treatment for another cancer or due to other medical condition (e.g. methotrexate exposure for treatment of rheumatoid arthritis).
  • * Previous central nervous system (CNS) radiation, intrathecal therapy or CNS-involved surgery.
  • * Participants with history of stroke, traumatic brain injury, brain surgery, Alzheimer's disease or other dementia.
  • * Participants with active substance abuse and/or in treatment for substance abuse, or history of bipolar disorder, psychosis, schizophrenia, ADHD, or learning disability.

Ages Eligible for Study

18 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

NRG Oncology,

Study Record Dates

2027-11-30