Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

Description

The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 20cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 20cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline.

Conditions

Macromastia, Post-operative Pain

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Study Overview

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Study Details

Study overview

The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 20cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 20cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline.

Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

Condition
Macromastia
Intervention / Treatment

-

Contacts and Locations

Farmington

Connecticut Children's, Farmington, Connecticut, United States, 06032

Hartford

Connecticut Children's, Hartford, Connecticut, United States, 06106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Female
  • 2. Age 13-21 at the time of surgery
  • 3. Undergoing bilateral reduction mammaplasty at Connecticut Children's from 1/1/2022-12/31/2025.
  • 4. Ability of child's parent/legal guardian to understand and the willingness to sign a written informed consent document.
  • 1. Patients with history of substance use disorder or "chronic pain" defined as pain requiring management and treatment by a pain management specialist.
  • 2. Patients already taking narcotics at the time of surgery.
  • 3. Patients with a history of hepatic or renal dysfunction.
  • 4. Patients with known allergy to bupivacaine.
  • 5. Patients who are pregnant, determined by urine testing in pre-operative area.
  • 6. Patients who are non-verbal or have developmental delays that would result in inability to report reliable pain scores.
  • 7. Patients with significant post-operative complications
  • 8. Patients not meeting inclusion criteria.
  • 9. Patients lost to follow-up- they must be seen within 1 week and 4 weeks post-operatively

Ages Eligible for Study

13 Years to 25 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Connecticut Children's Medical Center,

Christopher Hughes, MD, MPH, PRINCIPAL_INVESTIGATOR, Connecticut Children's

Study Record Dates

2026-04-01