RECRUITING

Neuroimaging of Opioid Phase (OPAL)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Official Title

Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord

Quick Facts

Study Start:2023-06-01
Study Completion:2027-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05905419

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Amy Westerhoff, BS
CONTACT
919-684-3161
chronicpainresearch@duke.edu
Edna Evington, PhD
CONTACT
919-684-2758
edna.evington@duke.edu

Principal Investigator

Katherine T Martucci, PhD
PRINCIPAL_INVESTIGATOR
Duke University

Study Locations (Sites)

Duke University Medical Center
Durham, North Carolina, 27710
United States

Collaborators and Investigators

Sponsor: Duke University

  • Katherine T Martucci, PhD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-01
Study Completion Date2027-06-30

Study Record Updates

Study Start Date2023-06-01
Study Completion Date2027-06-30

Terms related to this study

Keywords Provided by Researchers

  • fibromyalgia
  • women
  • brain
  • functional MRI
  • opioid
  • opiate
  • narcotic
  • chronic pain
  • pain

Additional Relevant MeSH Terms

  • Chronic Pain
  • Opioid Use