CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPTIVA-MRI study leverages the CAPTIVA trial design and implementation to capture information that will inform and facilitate the next generation of ICAS trials and the management of patients with ICAS.
Stroke, Intracranial Atherosclerotic Stenosis (ICAS)
CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPTIVA-MRI study leverages the CAPTIVA trial design and implementation to capture information that will inform and facilitate the next generation of ICAS trials and the management of patients with ICAS.
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
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University of Alabama Hospital, Birmingham, Alabama, United States, 35233
Baptist Medical Center Jacksonville, Jacksonville, Florida, United States, 32207
Jackson Memorial Hospital, Miami, Miami, Florida, United States, 33136
University of Illinois Hospital, Chicago, Illinois, United States, 60612
University of Chicago Medical Center, Chicago, Illinois, United States, 60637
Barnes Jewish Hospital, Saint Louis, Missouri, United States, 63108
Buffalo General Medical Center, Buffalo, New York, United States, 14203
North Shore University Hospita, Manhasset, New York, United States, 11030
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
Yale University,
David Liebeskind, MD, PRINCIPAL_INVESTIGATOR, University of California, Los Angeles
Sepideh Amin-Hanjani, MD, PRINCIPAL_INVESTIGATOR, University Hospitals
Rano Chatterjee, MD, PRINCIPAL_INVESTIGATOR, Washington University School of Medicine
2029-03-31