Enhancing Prospective Thinking in Early Recovery (PARK)

Description

The goal of this clinical trial is to demonstrate the commercial potential for a novel virtual reality (VR) intervention in preparation for Phase II development. This clinical trial will test the VR intervention for efficacy in reducing opioid use, increasing abstinence, and other self-reported and behavioral focus on future outcomes in individuals in early recovery from opioid use disorder. * Will the VR group, compared to the control group, have a lower number of opioid use days? * Will the VR group, compared to the control group, have longer periods of abstinence at the 30-day follow-up? * Will the VR group, compared to the control group, have significantly increased opioid abstinence rates? * Will the VR group, compared to baseline and the control group, show increased future self-identification post-VR intervention? * Will the VR group, compared to baseline and the control group, show increased future orientation post-VR intervention? * Will the VR group, compared to baseline and the control group, show an increased preference for delayed rewards in a laboratory delay discounting task post-VR intervention? * Will the VR group, compared to baseline and the control group, exceed in behavioral effects (i.e., future self-identification, future orientation, and increased preference for delayed rewards) at the 30-day follow-up? Researchers will compare the VR test group and the control group to see if there are differences in the results for the questions outlined above.

Conditions

Opioid Use, Opioid Use Disorder, Substance Use Disorders

Study Overview

Study Details

Study overview

The goal of this clinical trial is to demonstrate the commercial potential for a novel virtual reality (VR) intervention in preparation for Phase II development. This clinical trial will test the VR intervention for efficacy in reducing opioid use, increasing abstinence, and other self-reported and behavioral focus on future outcomes in individuals in early recovery from opioid use disorder. * Will the VR group, compared to the control group, have a lower number of opioid use days? * Will the VR group, compared to the control group, have longer periods of abstinence at the 30-day follow-up? * Will the VR group, compared to the control group, have significantly increased opioid abstinence rates? * Will the VR group, compared to baseline and the control group, show increased future self-identification post-VR intervention? * Will the VR group, compared to baseline and the control group, show increased future orientation post-VR intervention? * Will the VR group, compared to baseline and the control group, show an increased preference for delayed rewards in a laboratory delay discounting task post-VR intervention? * Will the VR group, compared to baseline and the control group, exceed in behavioral effects (i.e., future self-identification, future orientation, and increased preference for delayed rewards) at the 30-day follow-up? Researchers will compare the VR test group and the control group to see if there are differences in the results for the questions outlined above.

Enhancing Prospective Thinking in Early Recovery

Enhancing Prospective Thinking in Early Recovery (PARK)

Condition
Opioid Use
Intervention / Treatment

-

Contacts and Locations

Indianapolis

Indiana University School of Medicine - Goodman Hall, Indianapolis, Indiana, United States, 46202

Indianapolis

IUSM - Goodman Hall, Indianapolis, Indiana, United States, 46202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Abstinence between ≥14 days and ≤ 1 year
  • * 18-60 years old
  • * Verbal endorsement of commitment to recovery
  • * Outpatient
  • * Psychotropic drugs for SUD-comorbidity
  • * Mu-Opioid drugs
  • * Drug/alcohol abstinence ≥ 24 hours at the time of the study day visit
  • * English comprehension
  • * Unstable medical disorders
  • * Outside the age range of 18-60
  • * Habitual drug use
  • * Smell/taste disorders
  • * Unstable psychiatric conditions
  • * Extravagant/elaborate face tattoos

Ages Eligible for Study

18 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Indiana University,

Brandon G Oberlin, PhD, PRINCIPAL_INVESTIGATOR, Indiana University

Study Record Dates

2025-09-01