RECRUITING

The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are: 1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women? 2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women? 3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?

Official Title

The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults

Quick Facts

Study Start:2023-02-08
Study Completion:2026-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05912348

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-30 years of age
  2. * Recreationally active completing 75-150 minutes of moderate-to-vigorous intensity exercise (\>2 days/week).
  3. * Fair cardiorespiratory fitness levels (Men: VO2\>38.4 ml/kg/min; Women: VO2\>32.6 ml/kg/min).
  1. * Hypertension (resting or diagnosed)
  2. * Impaired fasting blood glucose (\>100mg/dL)
  3. * Diagnosed cardiovascular disease
  4. * Diagnosed diabetes
  5. * Diagnosed cancer
  6. * Diagnosed chronic kidney disease
  7. * Diagnosed musculoskeletal disorders that prevents the individual from exercising on a bike.

Contacts and Locations

Study Contact

Michael Brian, PhD
CONTACT
603-714-8899
Michael.Brian@unh.edu

Principal Investigator

Michael S Brian, PhD
PRINCIPAL_INVESTIGATOR
University of New Hampshire

Study Locations (Sites)

University of New Hampshire Cardiometabolic Research Laboratory
Durham, New Hampshire, 03824
United States

Collaborators and Investigators

Sponsor: University of New Hampshire

  • Michael S Brian, PhD, PRINCIPAL_INVESTIGATOR, University of New Hampshire

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-08
Study Completion Date2026-09-30

Study Record Updates

Study Start Date2023-02-08
Study Completion Date2026-09-30

Terms related to this study

Additional Relevant MeSH Terms

  • Insulin Resistance
  • Impaired Glucose Tolerance
  • Obesity
  • Metabolic Disturbance