Gravitas Feeding Tube System Placement Validation in Neonates

Description

The purpose of this study is to validate the Gravitas Feeding Tube System Placement Algorithm for NICU patients and to evaluate the safety and effectiveness of the Gravitas Feeding Tube in the neonate population for the administration of nutrition, fluids and medications.

Conditions

Nasogastric Tube

Study Overview

Study Details

Study overview

The purpose of this study is to validate the Gravitas Feeding Tube System Placement Algorithm for NICU patients and to evaluate the safety and effectiveness of the Gravitas Feeding Tube in the neonate population for the administration of nutrition, fluids and medications.

Gravitas Feeding Tube System Placement Validation in Neonates

Gravitas Feeding Tube System Placement Validation in Neonates

Condition
Nasogastric Tube
Intervention / Treatment

-

Contacts and Locations

Stanford

Lucile Packard (Stanford) Children's Hospital, Stanford, California, United States, 94303

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Charlottesville

University of Virginia Children's Health, Charlottesville, Virginia, United States, 22903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Infants in the Newborn Intensive Care Unit or on the general medical floor requiring a 5-8 Fr NG tube. The desired size of the feeding tube should be determined clinically, and the Gravitas 5-8 Fr Feeding Tube should only be placed if that size is appropriate.
  • * Age at enrollment: 0 to 18 weeks post-partum. Can be up to 12 weeks preterm (gestational age ≥ 28 weeks).
  • * Suitable to start enteral (gastric but not post-pyloric) feeding
  • * Anticipated to receive enteral feeding (either bolus or continuous feeds) for more than 6 hours. If enteral nutrition has already been initiated, indicated for replacement of an orogastric/nasogastric feeding tube.
  • * Ability to have a legally authorized representative provide informed consent Both neonates on a ventilator (non-invasive or invasive ventilation) or not requiring a ventilator are eligible for this study.
  • * Known major upper airway malformation (e.g. tracheoesophageal fistula)
  • * Known major GI malformation (e.g. malrotation)
  • * NPO status - neonate expected to remain NPO/NPG for the following 72 hours
  • * Has a medical condition that drastically affects gastric acid-secretion (e.g. Zollinger-Ellison Syndrome, congenital achlorhydria, gastrointestinal perforation/leak/obstruction);
  • * Has had removal of part of the stomach
  • * Critically ill, facing imminent death
  • * Neonate on ECMO
  • * Deemed unsuitable for enrollment in study by the site principal investigator based on the patients' medical history
  • * Infant needs an MRI in the immediate future (e.g. 6-12h)
  • * Infant needs post-pyloric feeds (distal to stomach)
  • * Infant has a basilar skull fracture

Ages Eligible for Study

0 Weeks to 18 Weeks

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Gravitas Medical, Inc.,

Study Record Dates

2024-12