Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Description

The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.

Conditions

Gestational Diabetes

Study Overview

Study Details

Study overview

The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Condition
Gestational Diabetes
Intervention / Treatment

-

Contacts and Locations

Iowa City

University of Iowa, Iowa City, Iowa, United States, 52242

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * ≥12 weeks and ≤5 years postpartum
  • * history of GDM or healthy pregnancy
  • * prediabetes or diabetes (HbA1c ≥5.7%)
  • * current tobacco use
  • * cardiovascular or metabolic disease
  • * cardiovascular or metabolic medication
  • * history of hypertension during pregnancy
  • * current pregnancy

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Anna Stanhewicz, PhD,

Anna Stanhewicz, PhD, PRINCIPAL_INVESTIGATOR, University of Iowa

Study Record Dates

2029-07