RECRUITING

Project 3: ACHIEVE- CHD

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health disparities and downstream Black-White lifespan inequality in two cities: Detroit, Michigan, and Cleveland, Ohio. The ACHIEVE GREATER Center will involve three separate but related projects that aim to mitigate health disparities in risk factor control for three chronic conditions, hypertension (HTN, Project 1), heart failure (HF, Project 2) and coronary heart disease (CHD, Project 3), which drive downstream lifespan inequality. All three projects will involve the use of Community Health Workers (CHWs) to deliver an evidence-based practice intervention program called PAL2. All three projects will also utilize the PAL2 Implementation Intervention (PAL2-II), which is a set of structured training and evaluation strategies designed to optimize CHW competence and adherence (i.e., fidelity) to the PAL2 intervention program. The present study is Project 3 of the ACHIEVE GREATER Center.

Official Title

ACHIEVE GREATER: Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region

Quick Facts

Study Start:2022-08-15
Study Completion:2027-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05918380

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. 40 to 75 years of age
  2. 2. Self-identified as Black or African American
  3. 3. Residence in the Cleveland Metro Area
  4. 4. Must have at least two of the following risk factors identified at a UH health fair screenings, with one risk factor being with SBP, A1c, or LDL:
  5. 1. BMI≥30 mg/dL
  6. 2. History of smoking
  7. 3. Elevated blood pressure defined as SBP\>140 or DBP\>80 mmHg
  8. 4. HbA1c≥5.7%
  9. 5. LDL≥130
  10. 5. Able to complete a coronary artery calcium score test (CAC)
  11. 6. Willing and able to consent
  12. 7. Willing to have a UH provider and UH care
  13. 8. Currently insured for standard of care procedures
  1. 1. Established documented cardiovascular disease (coronary artery disease, peripheral artery disease, myocardial infarction, stroke).
  2. 2. Systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg
  3. 3. Lung disease requiring supplemental oxygen therapy
  4. 4. Individuals receiving treatment for cancer related disease
  5. 5. Pregnant or nursing mothers

Contacts and Locations

Study Contact

Sanjay Rajagopalan, MD
CONTACT
216-844-5191
Sanjay.Rajagopalan@uhhospitals.org
Heidi Osborne
CONTACT
216-844-2833
heidi.osborne@uhhospitals.org

Principal Investigator

Sanjay Rajagopalan, MD
PRINCIPAL_INVESTIGATOR
University Hospitals Cleveland Medical Center

Study Locations (Sites)

University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106
United States

Collaborators and Investigators

Sponsor: University Hospitals Cleveland Medical Center

  • Sanjay Rajagopalan, MD, PRINCIPAL_INVESTIGATOR, University Hospitals Cleveland Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-15
Study Completion Date2027-01-01

Study Record Updates

Study Start Date2022-08-15
Study Completion Date2027-01-01

Terms related to this study

Keywords Provided by Researchers

  • Health Disparities
  • African American
  • Prevention
  • Coronary Heart Disease

Additional Relevant MeSH Terms

  • Coronary Heart Disease