RECRUITING

Nasal Obstruction and Olfactory Losses

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to these symptoms. The proposed study aims to develop novel clinical tools to better evaluate and relieve patients' nasal obstructive symptoms and to enable patients and clinicians to make more informed, personalized decisions regarding treatment strategy.

Official Title

Novel Mechanisms and Therapeutic Approaches for Nasal Obstruction and Olfactory Losses

Quick Facts

Study Start:2023-01-25
Study Completion:2028-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05920330

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Smell Loss complaints
  2. 2. Nasal Obstruction
  1. 1. Congenital olfactory losses
  2. 2. Nasal polyps, blocking the olfactory cleft
  3. 3. Significant atrophy
  4. 4. Cystic fibrosis
  5. 5. Wegeners or any other connective tissue disorder
  6. 6. Head trauma

Contacts and Locations

Study Contact

Veronica Formanek, BS
CONTACT
630-501-8168
Veronica.Formanek@osumc.edu
Beth Miles-Markley, MS
CONTACT
614-366-9244
Beth.Miles-Markley@osumc.edu

Principal Investigator

Kai Zhao, Ph.D
PRINCIPAL_INVESTIGATOR
Associate Professor

Study Locations (Sites)

Eye and Ear Institute, 915 Olentangy River Road, ENT, Suite 4000
Columbus, Ohio, 43212
United States

Collaborators and Investigators

Sponsor: Ohio State University

  • Kai Zhao, Ph.D, PRINCIPAL_INVESTIGATOR, Associate Professor

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-25
Study Completion Date2028-12-31

Study Record Updates

Study Start Date2023-01-25
Study Completion Date2028-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Nasal Obstruction