Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses

Description

The purpose of the study is to test a new video device for actinic keratoses. The device takes images of your skin lesions during the treatment, to learn whether this device can predict how well the treatment is working.

Conditions

Actinic Keratoses

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Study Overview

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Study Details

Study overview

The purpose of the study is to test a new video device for actinic keratoses. The device takes images of your skin lesions during the treatment, to learn whether this device can predict how well the treatment is working.

Noninvasive Imaging Techniques to Monitor Photosensitizer and Singlet Oxygen Levels During Photodynamic Therapy of Actinic Keratoses

Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses

Condition
Actinic Keratoses
Intervention / Treatment

-

Contacts and Locations

Cleveland

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States, 44195

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants who have at least 10 Actinic Keratoses lesions on the arms of legs, and with two AK lesions close enough to be seen together within a selected region of interest (ROI)
  • * Participants must be able to understand and are willing to sign a written informed consent document
  • * Female participants cannot be or become pregnant, nor can be nursing while on this study
  • * Using any topical treatment on their AKs; must stop at least one month prior
  • * Currently undergoing treatment for other cancers with medical or radiation therapy
  • * Patients with a known hypersensitivity to 5-aminolevulinic acid or any component of the study material
  • * Patients with history of a photosensitivity disease, such as porphyria cutanea tarda

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Case Comprehensive Cancer Center,

Edward Maytin, MD, PhD, PRINCIPAL_INVESTIGATOR, Cleveland Clinic, Case Comprehensive Cancer Center

Study Record Dates

2025-05-22