RECRUITING

Modulation of Brain Oscillations Underlying Working Memory

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory. tACS is a noninvasive method used to modulate the timing and patterns of brain rhythms via weak electric currents passed through electrodes on the scalp.

Official Title

State-dependent Modulation of Interactions of Theta and Gamma Rhythms in Working Memory

Quick Facts

Study Start:2024-07-10
Study Completion:2026-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05923606

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Able to provide informed consent
  2. * Fluent in English.
  1. * History of a neurological/psychiatric disorder
  2. * Current use of psychotropic medications
  3. * Current use of substances and drugs that were shown to affect tES (transcranial electrical stimulation) efficacy (dopamine altering drugs, nicotine, NMDA (N-methyl-D-aspartate) antagonists/agonists, sodium/calcium channel blockers, norepinephrine reuptake inhibitors, GABAergic modulators and selective serotonin reuptake inhibitors)
  4. * Contraindications for tACS (e.g., history of seizures, metallic implants in the head or neck, implanted brain stimulators, vagus nerve stimulators, pacemakers, pregnancy)

Contacts and Locations

Study Contact

Alexandra O'Neill, B.S.
CONTACT
(617) 726-8753
agoneill@mgh.harvard.edu
Hamdi Eryilmaz, Ph.D.
CONTACT
(617) 643-7462
hamdi.eryilmaz@mgh.harvard.edu

Principal Investigator

Hamdi Eryilmaz, Ph.D.
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Martinos Center for Biomedical Imaging
Charlestown, Massachusetts, 02129
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Hamdi Eryilmaz, Ph.D., PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-10
Study Completion Date2026-08-31

Study Record Updates

Study Start Date2024-07-10
Study Completion Date2026-08-31

Terms related to this study

Keywords Provided by Researchers

  • Working memory
  • Attention
  • Theta oscillations
  • Transcranial Alternating Current Stimulation

Additional Relevant MeSH Terms

  • Working Memory