Characterization of Gastric Evoked Potentials

Description

This is an exploratory study that will determine and standardize how best to record gastric evoked potentials (GEPs) elicited by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS), by optimizing the TMS parameters and cortical sites necessary to evoke GEPs.

Conditions

Healthy

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Study Overview

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Study Details

Study overview

This is an exploratory study that will determine and standardize how best to record gastric evoked potentials (GEPs) elicited by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS), by optimizing the TMS parameters and cortical sites necessary to evoke GEPs.

Characterization of Gastric Evoked Potentials

Characterization of Gastric Evoked Potentials

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States, 15232

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * psychosis or altered cognitive status
  • * history of head injury, metal in the skull, stroke, or a history of seizures, loss of consciousness or syncope
  • * implantable devices, such as a pacemaker or nerve stimulator
  • * current use of antiepileptic medications or current use of the following medications or substances which are known to lower the seizure threshold: Clozapine (Clozaril), Chlorpromazine (Thorazine), amphetamines or methamphetamine, Ecstasy, Ketamine, Angel Dust/PCP, cocaine, or 3 or more alcoholic drinks per day
  • * pregnancy
  • * BMI \> 30
  • * history of bariatric surgery such as sleeve gastrectomy or Roux-en-Y gastric bypass
  • * diabetes
  • * suffering from a neurodegenerative disorder.

Ages Eligible for Study

21 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Pittsburgh,

David J Levinthal, MD PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2026-07