RECRUITING

MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

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Conditions

MotivationMemorySelf-regulation

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research study is to understand how healthy individuals self-regulate motivation by observing brain activity using magnetic resonance imaging (MRI).

Official Title

Bridging Scales to Understand Endogenous Neuromodulation and Its Regulation

Quick Facts

Study Start:2023-07-30
Study Completion:2026-09-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05929898

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age between 18 and 45 years
  2. * Male or female
  3. * Right-handed
  4. * In good general health
  5. * Women of childbearing capacity: use of effective method of birth control
  1. * Current or diagnosis within past six months of an DSM-V Axis I or Axis II disorder (self-reported)
  2. * Current or past six month use of prescription medications indicated for psychiatric conditions (e.g.,depression, anxiety)
  3. * Current serious medical illness (self-reported)
  4. * Head injury resulting in loss of consciousness
  5. * For participants age \> 59 years, a total scaled score \< 8 on the Dementia Rating Scale-2.
  6. * A clinically-defined neurological disorder including, but not limited to:
  7. * Any condition likely to be associated with increased intracranial pressure
  8. * Space occupying brain lesion
  9. * History of stroke
  10. * Transient ischemic attack within two years
  11. * Cerebral aneurysm
  12. * Dementia
  13. * Mini Mental Status Exam (MMSE) score of \<24
  14. * Parkinson's disease
  15. * Huntington's disease
  16. * Multiple sclerosis
  17. * Presence of cochlear implants or other implanted electronic devices or non-removable metal (e.g., non-removable piercing, IUD)
  18. * History of an eye injury involving metal. Participants who worked with metal may be allowed to participate on a case-by-case basis with prior written approval from BIAC.
  19. * Claustrophobia or unwillingness to tolerate the confinement associated with being in the MRI scanner.
  20. * Weight of more than 250 pounds

Contacts and Locations

Study Contact

Laura Yost
CONTACT
919-681-4601
laura.yost@duke.edu
R. Alison Adock, MD, PhD
CONTACT
919-681-4601
alison.adcock@duke.edu

Principal Investigator

R. Alison Adock, MD, PhD
PRINCIPAL_INVESTIGATOR
Duke University

Study Locations (Sites)

Center for Cognitive Neuroscience
Durham, North Carolina, 27708
United States

Collaborators and Investigators

Sponsor: Duke University

  • R. Alison Adock, MD, PhD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-30
Study Completion Date2026-09-09

Study Record Updates

Study Start Date2023-07-30
Study Completion Date2026-09-09

Terms related to this study

Additional Relevant MeSH Terms

  • Motivation
  • Memory
  • Self-regulation