A Study of Glycemic Control in Left Ventricular Assist

Description

The study is being conducted to understand if the hemoglobin A1c, a measurement of control of blood sugars over a 3-month time, is valid in patients with Left Ventricular Assist Devices (LVADs) in place. To understand whether it is an adequate measurement, the investigators will compare the A1c to results from a continuous glucose monitor (CGM) measurement of blood sugars. By monitoring blood sugars continuously, the investigators will also assess whether they can get better control of blood sugars with a CGM, including avoiding low blood sugars.

Conditions

Type 2 Diabetes Mellitus, Hyperglycemia, Hypoglycemia

Study Overview

Study Details

Study overview

The study is being conducted to understand if the hemoglobin A1c, a measurement of control of blood sugars over a 3-month time, is valid in patients with Left Ventricular Assist Devices (LVADs) in place. To understand whether it is an adequate measurement, the investigators will compare the A1c to results from a continuous glucose monitor (CGM) measurement of blood sugars. By monitoring blood sugars continuously, the investigators will also assess whether they can get better control of blood sugars with a CGM, including avoiding low blood sugars.

GLYcemic Control Evaluation by Continuous Glucose Monitor Compared With a1C in Left Ventricular Assist Device-supported Patients (GLYCEM1C-LVAD)

A Study of Glycemic Control in Left Ventricular Assist

Condition
Type 2 Diabetes Mellitus
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Prior implantation of contemporary, centrifugal flow LVAD (HeartWare or HeartMate 3) at any time after 2010
  • * Diagnosis of type II diabetes mellitus
  • * Any antihyperglycemic regimen
  • * Greater than 3 months out from LVAD implantation
  • * Capable of utilizing smartphone device for LibreLink app for uploading glycemic data
  • * Patients may be enrolled who have preexisting CGM in place.
  • * Type I diabetics
  • * Unable to return at 3 month evaluation
  • * Unwillingness to participate

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Andrew Rosenbaum, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-07