Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Description

The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.

Conditions

Obsessive-Compulsive Disorder

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Study Overview

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Study Details

Study overview

The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Condition
Obsessive-Compulsive Disorder
Intervention / Treatment

-

Contacts and Locations

Stanford

Department of Psychiatry & Behavioral Sciences, Stanford, California, United States, 94305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Ages 18-65
  • * Meet the criteria for OCD diagnosis
  • * Failed at least 1 prior trial of standard first-line OCD treatment
  • * Agree to the following lifestyle modifications: comply with requirements for fasting prior to the Experimental Session, not enroll in any other interventional clinical trials during the duration of the study, and commit to medication study procedures.
  • * Able to provide informed consent
  • * prior naltrexone or ketamine use/exposure
  • * Any current or past medical/psychiatric condition that makes participation unsafe in the opinion of the investigator or study physician
  • * Pregnant or nursing, or able to become pregnant and are not practicing an effective means of birth control
  • * the presence of metal in the body that is contraindicated for MRI scans

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Stanford University,

Study Record Dates

2028-11