Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Description

The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.

Conditions

Dementia, Alzheimer Disease, Infections

Study Overview

Study Details

Study overview

The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.

Trial to Reduce Antimicrobial Use In Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0 (TRAIN-AD 2.0)

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Condition
Dementia
Intervention / Treatment

-

Contacts and Locations

Boston

Hebrew SeniorLife, Boston, Massachusetts, United States, 02131

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age \> 60
  • 2. A diagnosis of dementia (any type)
  • 3. Cognitive Functional Scale (CFS) \> 1
  • 4. NH length of stay \>90 days
  • 1. Less than 60 years of age
  • 2. Living in nursing home for less than 90 days
  • 3. Does not have diagnosis of dementia
  • 4. Does not meet CFS \>1 score

Ages Eligible for Study

60 Years to 106 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Hebrew SeniorLife,

Susan Mitchell, MD, MPH, PRINCIPAL_INVESTIGATOR, Hebrew SeniorLife

Study Record Dates

2026-06-30