A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

Description

The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.

Conditions

Anesthesia

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Study Overview

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Study Details

Study overview

The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.

Changes in Loading Conditions on Induction of General Anesthesia: Mechanisms of Post-Induction Hypotension (PIH)

A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

Condition
Anesthesia
Intervention / Treatment

-

Contacts and Locations

New York

Memorial Sloan Kettering Cancer Center (All protocol activites), New York, New York, United States, 10065

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adult patients ≥ 18 years of age requiring general anesthesia for surgery
  • * Intubation required for anesthetic management / surgery
  • * Anticipated prep time before incision of 20 minutes
  • * Baseline MAP \>70mmHg
  • * History of coronary artery disease
  • * History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)
  • * History of peripheral artery occlusive disease
  • * Beta-blocker use
  • * Anti-hypertensive medication use
  • * Patients with epidural, spinal, paravertebral, serratus blocks preoperatively
  • * Patients requiring rapid sequence induction (where intubation occurs concurrently with induction)
  • * Emergency surgery

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Memorial Sloan Kettering Cancer Center,

Anahita Dabo-Trubelja, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

2027-07