Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living

Description

This single-arm pilot study will evaluate the effects of an intervention to reduce exposure to unnecessary or potentially harmful medications among residents with dementia living in an assisted living facility. The goal of the intervention is to safely deprescribe medications (defined by dose reductions and stopped medications), based on a combination of clinical criteria and resident/surrogate preferences. The investigators will evaluate the effects of the intervention on the total number of medications deprescribed from enrollment at 30, 60, and 90 days along with resident/surrogate reports of quality of life at enrollment and 90 days.

Conditions

Polypharmacy, Dementia, Quality of Life

Study Overview

Study Details

Study overview

This single-arm pilot study will evaluate the effects of an intervention to reduce exposure to unnecessary or potentially harmful medications among residents with dementia living in an assisted living facility. The goal of the intervention is to safely deprescribe medications (defined by dose reductions and stopped medications), based on a combination of clinical criteria and resident/surrogate preferences. The investigators will evaluate the effects of the intervention on the total number of medications deprescribed from enrollment at 30, 60, and 90 days along with resident/surrogate reports of quality of life at enrollment and 90 days.

Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living

Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living

Condition
Polypharmacy
Intervention / Treatment

-

Contacts and Locations

Nashville

Abe's Garden Community, Nashville, Tennessee, United States, 37027

Nashville

NHC At The Trace, Nashville, Tennessee, United States, 37221

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Resident of assisted living facility
  • * Speaks English (due to interview-based assessments)
  • * Diagnosis of dementia
  • * Taking a total of 5 medications or at least one potentially inappropriate medication (defined by the Beers criteria, STOPP criteria, and the Rationalization of home medication by an Adjusted STOPP in older Patients \[RASP\])
  • * Able self-consent or has a proxy (surrogate)

Ages Eligible for Study

65 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Vanderbilt University,

Study Record Dates

2025-08-31