RECRUITING

Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG-Preschool Age

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Individuals with Fragile X Syndrome show differences in how they understand and learn language from infancy. They frequently have lifelong delays in speech and language as well. In addition, they experience other auditory symptoms, including being very sensitive to certain sounds as well as being more sensitive than others to loud sounds. The underlying brain activity for sound perception and speech learning in Fragile X is not well understood, especially in the infant, toddler, and preschool years. This study uses behavioral assessment of speech and language abilities, neuroimaging, and hearing tests to understand how speech and hearing are different in children with Fragile X Syndrome.

Official Title

Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Preschool Age

Quick Facts

Study Start:2022-10-04
Study Completion:2025-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05957549

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:24 Months to 4 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Diagnoses of Fragile X Syndrome, Typical Development, or History of Premature Birth
  2. * able to sit independently
  3. * English is spoken at home
  1. * For all participants: no seizures in the past 6 months
  2. * For typical development group and Fragile X group: not born prior to 32 weeks gestation

Contacts and Locations

Study Contact

Elizabeth Smith, PhD
CONTACT
5135171383
elizabeth.smith3@cchmc.org
Craig Erickson, MD
CONTACT
5136366553
craig.erickson@cchmc.org

Study Locations (Sites)

Cincinnati Children'S Hospital
Cincinnati, Ohio, 45229
United States

Collaborators and Investigators

Sponsor: Children's Hospital Medical Center, Cincinnati

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-10-04
Study Completion Date2025-08-31

Study Record Updates

Study Start Date2022-10-04
Study Completion Date2025-08-31

Terms related to this study

Additional Relevant MeSH Terms

  • Fragile X Syndrome