RECRUITING

MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after treatment with definitive-intent chemoradiotherapy for patients with locally advanced cervical and pancreatic cancer.

Official Title

MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial (METEOR-CRATR)

Quick Facts

Study Start:2024-01-11
Study Completion:2032-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05975593

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Confirmation of intent to receive radiotherapy for one of the following diagnoses:
  2. * Cervical cancer
  3. * Pancreatic cancer
  4. * ECOG performance status ≤ 2
  5. * At least 18 years old
  6. * Able to understand and willing to sign an IRB-approved written informed consent document
  1. * Any issue (medical, anatomic, other) that might preclude safe acquisition of biospecimens at the discretion of the treating physician

Contacts and Locations

Study Contact

Cliff Robinson, M.D.
CONTACT
314-362-8567
clifford.robinson@wustl.edu

Principal Investigator

Cliff Robinson, M.D.
PRINCIPAL_INVESTIGATOR
Washington University School of Medicine

Study Locations (Sites)

Washington University School of Medicine
Saint Louis, Missouri, 63110
United States

Collaborators and Investigators

Sponsor: Washington University School of Medicine

  • Cliff Robinson, M.D., PRINCIPAL_INVESTIGATOR, Washington University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-11
Study Completion Date2032-12-31

Study Record Updates

Study Start Date2024-01-11
Study Completion Date2032-12-31

Terms related to this study

Keywords Provided by Researchers

  • Radiotherapy
  • Chemotherapy
  • Cervical cancer
  • Pancreatic cancer
  • Biospecimen

Additional Relevant MeSH Terms

  • Locally Advanced Cervical Carcinoma
  • Locally Advanced Cervical Cancer
  • Locally Advanced Pancreas Cancer
  • Locally Advanced Pancreatic Carcinoma
  • Locally Advanced Pancreatic Cancer
  • Cervical Cancer
  • Pancreas Cancer
  • Pancreatic Cancer
  • Cancer of the Cervix
  • Cancer of the Pancreas