A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

Description

Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.

Conditions

Gastroesophageal Reflux, Regurgitation, Heartburn

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Study Overview

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Study Details

Study overview

Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.

Breath Testing for Small Intestinal Bacterial Overgrowth in Patients Treated With Proton Pump Inhibitors

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

Condition
Gastroesophageal Reflux
Intervention / Treatment

-

Contacts and Locations

Jacksonville

Mayo Clinic Florida, Jacksonville, Florida, United States, 32224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Predominant symptoms of gastroesophageal reflux disease including heartburn, regurgitation
  • * Subjects must be able to give appropriate informed consent
  • * Prior diagnosis of SIBO
  • * Use of PPIs or H2R-anatagonstists in the prior 3 months
  • * Major concomitant illness (renal, hepatic, rheumatologic or cardiovascular disease, or malignancy)
  • * Antibiotic therapy within one month
  • * Prior gastrointestinal surgery including esophageal, gastric, and small or large bowel surgery
  • * Previously diagnosed irritable bowel syndrome or inflammatory bowel disease
  • * Individuals who are pregnant or breast feeding
  • * Patients with plans to become pregnant
  • * Inability to take PPIs, including allergy/sensitivity

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Andree Koop, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2024-12-31