RECRUITING

Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Through the proposed Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement (SCOPE) study, the investigators will design and evaluate an overdose prevention and HIV prevention study among people who use drugs (PWUD). Specifically, SCOPE will provide access to drug-checking services for PWUD to better understand the contents of the drug supply, in combination with PrEP for those who are HIV-, to both reduce overdose and HIV among PWUD in Baltimore City.

Official Title

Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

Quick Facts

Study Start:2023-07-28
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05977881

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years or older,
  2. * self-reports having used illicit stimulants or opioids at least once in the past 3 months,
  3. * self-reports being HIV negative
  4. * reports injection drug use in the past 6 months OR reports at least one of the following indicators of sexual HIV risk exposure in the past 6 months:
  5. 1. Sexually Transmitted Infection (STI) diagnosis in the past 6 months
  6. 2. "Condom-less" vaginal or anal sex in the past 6 months
  7. * Willing to provide a urine sample for urine drug screening of substances
  8. * Willing to undergo rapid HIV testing
  9. * Willing to undergo STI testing
  1. * Determined to be too high or drunk or cognitively impaired, less than 18 years of age
  2. * unwilling to provide all required biological specimens (Phase 3 only)
  3. * unwilling/unable to give consent

Contacts and Locations

Study Contact

Miles Morris, MPH
CONTACT
410-502-4435
mmorr100@jhu.edu
Susan G Sherman, PhD
CONTACT
410-614-3518
ssherman@jhu.edu

Principal Investigator

Susan Sherman, PhD
PRINCIPAL_INVESTIGATOR
Johns Hopkins Bloomberg School of Public Health

Study Locations (Sites)

Johns Hopkins School of Public Health
Baltimore, Maryland, 21205
United States

Collaborators and Investigators

Sponsor: Johns Hopkins Bloomberg School of Public Health

  • Susan Sherman, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins Bloomberg School of Public Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-28
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2023-07-28
Study Completion Date2026-06-30

Terms related to this study

Keywords Provided by Researchers

  • Drug Use
  • Overdose
  • PrEP
  • Harm Reduction

Additional Relevant MeSH Terms

  • HIV Infections