COMPLETED

Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine the magnitude of clinical benefit achieved through machine learning assisted radiation treatment planning (MLAP) on post-treatment clinical outcomes such as acute toxicity and patient reported outcomes.

Official Title

A Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning Versus Standard Radiation Treatment Planning

Quick Facts

Study Start:2023-08-07
Study Completion:2025-10-29
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT05979883

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age ≥ 18 years at time of registration
  2. * Receiving curative intent intensity modulated radiotherapy for head and neck primary cancer at the discretion of the treating medical doctor (MD)
  3. * Provide written informed consent or allow legally authorized representative to consent on behalf of a participant
  4. * Willing to return to enrolling institution for study follow-up visit
  1. * Incarcerated
  2. * Unable to provide informed consent
  3. * Prior Head and Neck (H\&N) radiation therapy
  4. * Planned radiation dosing LK\<30 Gy or \>76 Gy

Contacts and Locations

Principal Investigator

Daniel J. Ma, M.D.
PRINCIPAL_INVESTIGATOR
Mayo Clinic in Rochester

Study Locations (Sites)

Mayo Clinic in Arizona
Scottsdale, Arizona, 85259
United States
Mayo Clinic in Florida
Jacksonville, Florida, 32224
United States
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota, 56007
United States
Mayo Clinic Health Systems-Mankato
Mankato, Minnesota, 56001
United States
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin, 54701
United States
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin, 54601
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • Daniel J. Ma, M.D., PRINCIPAL_INVESTIGATOR, Mayo Clinic in Rochester

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-07
Study Completion Date2025-10-29

Study Record Updates

Study Start Date2023-08-07
Study Completion Date2025-10-29

Terms related to this study

Keywords Provided by Researchers

  • MLAP (Machine Learning Adaptive Planning)
  • RapidPlan

Additional Relevant MeSH Terms

  • Cancer Head Neck
  • Cancer, Head
  • Cancer Neck