RECRUITING

Goal Setting to Promote Physical Activity Adherence in Midlife Adults

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Conditions

Physical ActivityExercisemild cognitive impairmentAlzheimer's diseasedementiabehavior changemidlife

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD/ADRD). Yet nearly half of midlife adults (48%) do not meet national physical activity guidelines. The purpose of this mechanistic trial is to identify effective goal setting techniques to enhance psychosocial processes of self-regulation for the successful promotion of PA and adherence to national PA guidelines among midlife adults, with the long-term goal of reducing AD/ADRD risk

Official Title

Goal Setting to Promote Physical Activity Adherence in Midlife to Reduce Risk of Alzheimer's Disease and Related-Dementias: A Randomized Mechanistic Proof-Of-Concept Trial

Quick Facts

Study Start:2023-07-17
Study Completion:2027-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05980052

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:45 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Aged 45 to 65 years
  2. * BMI between 30 kg/m2 to 50 kg/m2
  3. * Participants must weigh a minimum of 110 pounds
  4. * Engaging in 60 minutes or less of self-reported moderate-to-vigorous physical activity at screening (based on Exercise Vital Sign Questionnaire)
  5. * Self-reported ownership of a smartphone with an iOS or Android operating system (necessary for participants to track their activity using a Fitbit activity monitor)
  1. * Endorsing an item on the Physical Activity Readiness Questionnaire (PAR-Q), unless a physician's note is provided
  2. * Resting blood pressure greater than 200/110 mmHG as assessed at the baseline study assessment (unless a physician's note is provided)
  3. * Pregnant or planning to become pregnant in next 8-months (Phase 1) or 12 months (Phase 2)
  4. * Plans to relocate out of metropolitan Phoenix, Arizona area in the next 8-months (Phase 1) or 12 months (Phase 2)
  5. * Participation in another physical activity, nutrition or weight loss program at time of screening or at any time during the intervention
  6. * Individuals with mild cognitive impairment (MCI), as determined by either a self-report of receiving a diagnosis of MCI from a health care provider or as assessed by the Montreal Cognitive Assessment (MoCA) at the study orientation session. A score \< 26 is an exclusion criterion for US born participants. A score of \<23 is an exclusion for participants born outside of the US who completed their high school education in a country where English is not the primary language.
  7. * Being previously prescribed one of the 5 approved Alzheimer's medications, including: Donepezil (Aricept), Rivastigmine (Exelon), Galantamine (Razadyne), Memantine (Namenda), Memantine + Donepezil (Namzaric)
  8. * Score of 16 or higher on the Center for Epidemiological Studies-Depression Scale (CES-D)
  9. * Self-reported current diagnosis of major depression
  10. * Currently taking 2 or more ant-depression drugs
  11. * History of stroke
  12. * Incarcerated individuals (i.e., Prisoners)

Contacts and Locations

Study Contact

Rodney Joseph, PhD
CONTACT
602-496-0772
rodney.joseph@asu.edu
Molly Maxfield, PhD
CONTACT
602-496-2311
molly.maxfield@asu.edu

Study Locations (Sites)

Arizona State University
Phoenix, Arizona, 85004
United States

Collaborators and Investigators

Sponsor: Arizona State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-17
Study Completion Date2027-01-01

Study Record Updates

Study Start Date2023-07-17
Study Completion Date2027-01-01

Terms related to this study

Keywords Provided by Researchers

  • exercise
  • physical activity
  • mild cognitive impairment
  • Alzheimer's disease
  • dementia
  • behavior change
  • midlife

Additional Relevant MeSH Terms

  • Physical Activity
  • Exercise