RECRUITING

Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine differences in pain, functional patient reported outcomes, and objective imaging parameters following non-operative and meniscus root repair treatment. Furthermore, the long-term goal of this research proposal is to understand the natural history of meniscal root tears and their subsequent repair, in order to better determine risk factors for inferior outcomes and progression to osteoarthritis (OA).

Official Title

Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Quick Facts

Study Start:2022-04-20
Study Completion:2026-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05985772

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * MRI-verified isolated tibial medial meniscus root tear
  2. * Subject must be 18 years of age or older
  1. * Concurrent ligamentous knee pathology requiring surgical intervention (i.e. anterior cruciate ligament tear, posterior cruciate ligament tear, posterolateral corner injury, high-grade medial collateral ligament tear),
  2. * Preoperative Kellgren-Lawrence grade of 3 or 4
  3. * Inability to complete outcome questionnaires or comply with required postoperative imaging or MRI requirements, or medical contraindications to surgery or physical therapy.
  4. * There will be no exclusion criteria regarding body mass index (BMI) or mechanical alignment, however subjects will be stratified in groups for further analysis (BMI less and over 35 and varus alignment below and over 3º of varus).
  5. * Pregnancy
  6. * Subjects \< 18 years of age

Contacts and Locations

Study Contact

Carla M. Edwards, PhD
CONTACT
312-563-5735
carla_edwards@rush.edu
Jorge Chahla, MD
CONTACT
(312) 432-2818
jorge.chahla@rushortho.com

Principal Investigator

Jorge Chahla, MD
PRINCIPAL_INVESTIGATOR
Rush University Medical Center Associate Professor and Surgeon

Study Locations (Sites)

Rush University Medical Center
Chicago, Illinois, 60612
United States

Collaborators and Investigators

Sponsor: Rush University Medical Center

  • Jorge Chahla, MD, PRINCIPAL_INVESTIGATOR, Rush University Medical Center Associate Professor and Surgeon

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-20
Study Completion Date2026-03

Study Record Updates

Study Start Date2022-04-20
Study Completion Date2026-03

Terms related to this study

Additional Relevant MeSH Terms

  • Meniscus Tear, Tibial