RECRUITING

Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is intended to investigate whether roux-en-y bypass surgery is superior to conventional loop gastrojejunostomy for Malignant gastric outlet obstruction in terms of tolerance to solid food intake. We hypothesize that roux-en-y bypass will be associated with improved solid food intake in the first 30 days after surgery.

Official Title

Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction

Quick Facts

Study Start:2023-08-17
Study Completion:2026-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05986890

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Provision of signed and dated informed consent form.
  2. 2. Stated willingness to comply with all study procedures and availability for the duration of the study.
  3. 3. Male or female aged ≥18 years old.
  4. 4. Patients with a diagnosis of malignant gastric outlet obstruction. i. Defined as malignant cancer growth of any organ origin in the area of the distal stomach or duodenum preventing normal gastric emptying as determined by symptoms and cross-sectional imaging studies.
  5. 5. Patients deemed to benefit from surgical bypass as opposed to stent placement, by the primary surgeon. This includes assessing participants survival chances and ability to undergo a surgical procedure.
  6. 6. Patients in a general health status that permits abdominal surgery under general anesthesia. As determined by primary surgeon and anesthesiologist.
  1. 1. Patients that have had previous treatment for malignant gastric outlet obstruction.
  2. 2. Patients with MGOO deemed to benefit more from endoscopic stent placement rather than surgery for symptom relief. This assessment will be at treating surgeon's discretion.

Contacts and Locations

Study Contact

G. Paul Wright, MD
CONTACT
616-486-6333
paul.wright@corewellhealth.org
Esther Peariso, MSN
CONTACT
6164860358
esther.peariso@corewellhealth.org

Principal Investigator

G. Paul Wright, MD
PRINCIPAL_INVESTIGATOR
Corewell Health

Study Locations (Sites)

G. Paul Wright
Grand Rapids, Michigan, 49503
United States

Collaborators and Investigators

Sponsor: Spectrum Health Hospitals

  • G. Paul Wright, MD, PRINCIPAL_INVESTIGATOR, Corewell Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-17
Study Completion Date2026-12-01

Study Record Updates

Study Start Date2023-08-17
Study Completion Date2026-12-01

Terms related to this study

Keywords Provided by Researchers

  • MGOO
  • Malignant gastric outlet obstruction
  • gastric outlet
  • malignant tumor
  • proximal bowel obstruction
  • bowel obstruction

Additional Relevant MeSH Terms

  • Malignant Gastric Outlet Obstruction