The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
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University of Arkansas for Medical Sciences (UAMS), Little Rock, Arkansas, United States, 72205
University of California San Francisco, San Francisco, California, United States, 94143
Stanford University, Stanford, California, United States, 94305
Yale School of Medicine, New Haven, Connecticut, United States, 06510
Massachusetts General Hospital, Boston, Massachusetts, United States, 02114
Brigham & Women's, Boston, Massachusetts, United States, 02115
University of Michigan, Ann Arbor, Michigan, United States, 48109
Henry Ford Health, Detroit, Michigan, United States, 48202
Washington University School of Medicine, Saint Louis, Missouri, United States, 63110
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States, 03756
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
Washington University School of Medicine,
Sachin Kheterpal, MD, PRINCIPAL_INVESTIGATOR, University of Michigan
Michael S Avidan, MBBCh, PRINCIPAL_INVESTIGATOR, Washington University School of Medicine
Allison Janda, MD, STUDY_DIRECTOR, University of Michigan
Mark Neuman, MD, STUDY_DIRECTOR, University of Pennsylvania
Bethany Pennington, PharmD, STUDY_DIRECTOR, Washington University School of Medicine
Douglas Colquhoun, MBChB, STUDY_DIRECTOR, University of Michigan
2028-07-31