Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Adults \>40 years of age
- * Pain at the thumb base brought on by direct pressure (grind test) and with movement
- * Pain resistant to previous conservative management (including over the counter medications (ibuprofen/acetaminophen), icing, splinting/braces, or topical analgesics)
- * Radiological observation indicative of arthritis based on the Eaton-Littler classification system (stages 1 through 4)
- * Patient understands the protocol and signed the informed consent
- * Patient is covered by health insurance
- * • Known allergy to either of the treatment products
- * Patient's analgesic treatment regimen or other modalities of managing symptoms/pain associated with their hand pathology was modified within four weeks before trial inclusion
- * Symptomatic Scaphoid-trapezial arthritis present
- * Localized or systemic infection
- * Previous thumb surgery on study thumb
- * Previous thumb injury on study thumb
- * Patient with inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis)
- * Severe and/or uncontrolled hypertension
- * De Quervain tendinopathy present
- * History of injection to the trapeziometacarpal joint on study thumb within the previous 6 weeks
- * Uncontrolled diabetes
- * Pregnant or lactating females. Female participants of childbearing potential must have a negative pregnancy test before the injection. Women without childbearing potential (ie., surgically sterile with hysterectomy and/or bilateral oophorectomy and/or bilateral salpingectomy OR ≥ 12 months of amenorrhea and at least 50 years of age) are eligible to participate without completing a pregnancy test.
- * Immunodeficient patients
- * Patients that are currently using nicotine products, or who have quit in the last 12 months
- * Patients under guardianship, curatorship, or are otherwise not self-sufficient
- * Patients participating in another clinical research trial which interferes with this study protocol or outcomes
- * Patients unable to follow the protocol in the investigators' judgement.
Ages Eligible for Study
40 Years to
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
No