RECRUITING

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Early detection of coronary atherosclerotic disease facilitates adequate prevention. The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography / computed tomography (NaF-PET/CT) with those of conventional and ultra-high-resolution-CT (UHR-CT) in patients with suspected coronary artery disease. For this purpose, the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT testing.

Official Title

PET/CT vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease

Quick Facts

Study Start:2023-07-01
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05994014

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Male or female patients
  2. * 18 years or older
  3. * referred for coronary CT angiography because of suspected coronary heart disease (CHD) with stable symptoms
  1. * The patient has a history of coronary heart disease, defined by prior myocardial infarction or prior coronary artery revascularization.
  2. * Pregnancy.
  3. * Atrial fibrillation.
  4. * Morbid obesity defines as a body mass index of \>40.
  5. * The patient has any other clinically significant medical condition that in the opinion of the Investigator could impact the patient's ability to successfully complete the trial.

Contacts and Locations

Study Contact

Armin A Zadeh, MD PhD MPH
CONTACT
410-502-0549
azadeh1@jhmi.edu
Tia Thomas, RN, BSN
CONTACT
410-955-5000
tthoma88@jh.edu

Principal Investigator

Armin Zadeh, MD PhD MPH
PRINCIPAL_INVESTIGATOR
Johns Hopkins School of Medicine

Study Locations (Sites)

Johns Hopkins Hospital
Baltimore, Maryland, 21287
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Armin Zadeh, MD PhD MPH, PRINCIPAL_INVESTIGATOR, Johns Hopkins School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-01
Study Completion Date2026-06

Study Record Updates

Study Start Date2023-07-01
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • coronary imaging
  • prevention
  • early detection

Additional Relevant MeSH Terms

  • Coronary Artery Disease
  • Atherosclerosis
  • Coronary Atherosclerosis of Native Coronary Artery