RECRUITING

Changes in Inhibition and Valuation After Eating

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.

Official Title

Dynamic Neural Computations Underlying Cognitive Control in Bulimia Nervosa

Quick Facts

Study Start:2023-12-12
Study Completion:2027-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05995496

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Female
  2. * Aged 18 to 45 years
  3. * Current BMI greater than or equal to 18.5kg/m2 but under 30kg/m2
  4. * Right-handed
  5. * English-speaking
  6. * Meet DSM-5 criteria for bulimia nervosa
  1. * Medical instability
  2. * Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation
  3. * Shift work
  4. * Pregnancy, planned pregnancy, or lactation during the study period
  5. * Allergy to any of the ingredients in or unwillingness to consume the standardized meal or unwillingness to drink water during the fasting period
  6. * Any contraindication for fMRI

Contacts and Locations

Study Contact

Jiulin Dai, B.S.
CONTACT
212-824-9561
jiulin.dai@mssm.edu
Alexa R Krugel, B.S
CONTACT
alexa.krugel@mssm.edu

Principal Investigator

Laura A Berner, Ph.D.
PRINCIPAL_INVESTIGATOR
Mount Sinai Icahn School of Medicine

Study Locations (Sites)

Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai
New York, New York, 10029
United States

Collaborators and Investigators

Sponsor: Icahn School of Medicine at Mount Sinai

  • Laura A Berner, Ph.D., PRINCIPAL_INVESTIGATOR, Mount Sinai Icahn School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-12
Study Completion Date2027-12-31

Study Record Updates

Study Start Date2023-12-12
Study Completion Date2027-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Bulimia Nervosa