Changes in Inhibition and Valuation After Eating

Description

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.

Conditions

Bulimia Nervosa

Study Overview

Study Details

Study overview

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.

Dynamic Neural Computations Underlying Cognitive Control in Bulimia Nervosa

Changes in Inhibition and Valuation After Eating

Condition
Bulimia Nervosa
Intervention / Treatment

-

Contacts and Locations

New York

Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai, New York, New York, United States, 10029

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Female
  • * Aged 18 to 45 years
  • * Current BMI greater than or equal to 18.5kg/m2 but under 30kg/m2
  • * Right-handed
  • * English-speaking
  • * Meet DSM-5 criteria for bulimia nervosa
  • * Medical instability
  • * Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation
  • * Shift work
  • * Pregnancy, planned pregnancy, or lactation during the study period
  • * Allergy to any of the ingredients in or unwillingness to consume the standardized meal or unwillingness to drink water during the fasting period
  • * Any contraindication for fMRI

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Icahn School of Medicine at Mount Sinai,

Laura A Berner, Ph.D., PRINCIPAL_INVESTIGATOR, Mount Sinai Icahn School of Medicine

Study Record Dates

2027-12-31