Transforming Hemodialysis-Related Vascular Access Education

Description

The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis vascular access. Study participants will each be assigned to one of the 3 approaches: 1) "Education", in which participants will be given a video and brochure that provide information about the types of vascular access and what can be expected before and after the vascular access is placed, 2) "Education-Plus", in which participants will be given the video and brochure and will also have sessions by telehealth with a motivational interviewing coach to provide additional support around vascular access placement, and 3) "Usual Care", in which participants will have the usual education provided by their kidney doctor and clinic staff just as if they were not in the study. Participants in all 3 groups will be asked to complete questionnaires by telephone and may be invited to be interviewed about their experience with the study intervention at the end of the study. Study participation will last for about 12 months, with most of the study activities taking place during the first 3 months.

Conditions

Chronic Kidney Disease, Hemodialysis Vascular Access

Study Overview

Study Details

Study overview

The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis vascular access. Study participants will each be assigned to one of the 3 approaches: 1) "Education", in which participants will be given a video and brochure that provide information about the types of vascular access and what can be expected before and after the vascular access is placed, 2) "Education-Plus", in which participants will be given the video and brochure and will also have sessions by telehealth with a motivational interviewing coach to provide additional support around vascular access placement, and 3) "Usual Care", in which participants will have the usual education provided by their kidney doctor and clinic staff just as if they were not in the study. Participants in all 3 groups will be asked to complete questionnaires by telephone and may be invited to be interviewed about their experience with the study intervention at the end of the study. Study participation will last for about 12 months, with most of the study activities taking place during the first 3 months.

Transforming Hemodialysis-Related Vascular Access Education (THRiVE)

Transforming Hemodialysis-Related Vascular Access Education

Condition
Chronic Kidney Disease
Intervention / Treatment

-

Contacts and Locations

Chapel Hill

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States, 27599

Philadelphia

University of Pennsylvania, Philadelphia, Pennsylvania, United States, 19106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age 18 years or older
  • 2. Nephrology visit for chronic kidney disease during the last 18 months
  • 3. Most recent eGFR less than or equal to 20 ml/min/1.73 m2 or 2-year Kidney Failure Risk Equation score greater than 40%
  • 4. Documentation in the medical record or confirmation from the treating nephrologist of a patient-nephrologist discussion about hemodialysis
  • 1. Planning for peritoneal dialysis, preemptive transplant, or conservative management of kidney failure
  • 2. Previous placement of an AV access
  • 3. Prior or scheduled appointment with surgeon for AV access evaluation or creation
  • 4. Cognitive dysfunction or severe visual impairment that prevents use of the education materials
  • 5. Does not speak either English or Spanish

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Laura M. Dember, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Jennifer E. Flythe, MD, MPH, PRINCIPAL_INVESTIGATOR, University of North Carolina, Chapel Hill

Deidra Crews, MD, ScM, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

2027-09-30