RECRUITING

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as other diseases. With this information, the researchers hope to characterize better the role of environmental pollutants on IBD and develop novel strategies towards prevention.

Official Title

PLANET: Exploring the Role of Plastics and Toxins in Intestinal Inflammation

Quick Facts

Study Start:2023-08-15
Study Completion:2025-06-16
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06001450

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * The ability to sign and date an informed consent form
  2. * Be pregnant, or wishing to become pregnant in the near future and enroll the infant that the individual is pregnant with
  3. * Aged 18 or older
  4. * English-speaking (this observational study uses non-validated questionnaires that are only available in English)
  5. * Of any ethnicity
  6. * Be a spouse, related household member (sibling, parent, etc.) or a child of an enrolled pregnant person
  1. * Individuals who are unable to give informed consent
  2. * Be diagnosed with a pregnancy complication, such as intrauterine fetal demise/stillbirth, preeclampsia, hyperemesis gravidarum, or have an active infection, including chorioamnionitis or sepsis.

Contacts and Locations

Study Contact

Mellissa Picker, BS
CONTACT
212-659-6710
mellissa.picker@mssm.edu

Principal Investigator

Manasi Agrawal, MD, MS
PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai

Study Locations (Sites)

Icahn School of Medicine at Mount Sinai
New York, New York, 10128
United States

Collaborators and Investigators

Sponsor: Icahn School of Medicine at Mount Sinai

  • Manasi Agrawal, MD, MS, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-15
Study Completion Date2025-06-16

Study Record Updates

Study Start Date2023-08-15
Study Completion Date2025-06-16

Terms related to this study

Keywords Provided by Researchers

  • microplastics
  • nanoplastics
  • pregnancy
  • pollution
  • environmental pollutants

Additional Relevant MeSH Terms

  • Crohns Disease
  • Pregnancy
  • Inflammatory Bowel Disease