Dynamic Airway CT is Diagnostic for Tracheomalacia in Children

Description

The purpose of this pilot interventional study is to evaluate the use of Dynamic Airway Computed Tomography (DA-CT) for diagnosis of tracheomalacia in children 0-18 years for whom flexible bronchoscopy has been performed. The primary aims are to evaluate the diagnostic accuracy, image quality, and radiation exposure of DA-CT as a potential noninvasive alternative to the gold standard of flexible bronchoscopy in the diagnosis of tracheomalacia. The results from this pilot study will help to estimate sample size for a larger-scale study with more precise estimates of DA-CT diagnostic potential.

Conditions

Tracheomalacia

Study Overview

Study Details

Study overview

The purpose of this pilot interventional study is to evaluate the use of Dynamic Airway Computed Tomography (DA-CT) for diagnosis of tracheomalacia in children 0-18 years for whom flexible bronchoscopy has been performed. The primary aims are to evaluate the diagnostic accuracy, image quality, and radiation exposure of DA-CT as a potential noninvasive alternative to the gold standard of flexible bronchoscopy in the diagnosis of tracheomalacia. The results from this pilot study will help to estimate sample size for a larger-scale study with more precise estimates of DA-CT diagnostic potential.

Dynamic Airway CT is Diagnostic for Tracheomalacia in Children

Dynamic Airway CT is Diagnostic for Tracheomalacia in Children

Condition
Tracheomalacia
Intervention / Treatment

-

Contacts and Locations

New York

Fink Children's Ambulatory Center/Hassenfeld Children's Center, New York, New York, United States, 10016

New York

Tisch Hospital, New York, New York, United States, 10016

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants 0-18 years old, with
  • * Clinically indicated flexible bronchoscopy has been performed
  • * Pregnancy or breastfeeding
  • * Unable to undergo CT scanning without sedation
  • * Patients with tracheostomy

Ages Eligible for Study

0 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

NYU Langone Health,

Eleanor Muise, MD, PRINCIPAL_INVESTIGATOR, NYU Langone Health

Study Record Dates

2025-06-30