Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums

Description

The primary objective of this randomized clinical trial is to compare the mean root coverage achieved with Coronally Advanced Flap (CAF) + Connective Tissue Graft (CTG) (control) to Gingival Pedicle Split Thickness flap (GPST) + CTG (test) for the treatment of isolated gingival recession defects in mandibular incisors. The secondary objectives are to compare the percentage of complete root coverage and keratinized tissue gain between the two techniques.

Conditions

Recession, Gingival

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Study Overview

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Study Details

Study overview

The primary objective of this randomized clinical trial is to compare the mean root coverage achieved with Coronally Advanced Flap (CAF) + Connective Tissue Graft (CTG) (control) to Gingival Pedicle Split Thickness flap (GPST) + CTG (test) for the treatment of isolated gingival recession defects in mandibular incisors. The secondary objectives are to compare the percentage of complete root coverage and keratinized tissue gain between the two techniques.

Comparison of Surgical Techniques to Treat Isolated Gingival Recession in Mandibular Incisors: A Randomized Clinical Trial

Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums

Condition
Recession, Gingival
Intervention / Treatment

-

Contacts and Locations

Cleveland

Case Western Reserve University School of Dental Medicine, Cleveland, Ohio, United States, 44106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Males and females of \> 18 years of age
  • * Single Cairo's RT1 (Recession Type 1) and RT2 ( Recession Type 2) recession defects (≥3 mm in depth) in mandibular anterior teeth (Incisors).
  • * Presence of identifiable cemento-enamel junction (CEJ)
  • * Presence of a step ≤1 mm at the CEJ level and/or the presence of a root abrasion, but with an identifiable CEJ, will be accepted
  • * Periodontally and systemically healthy patients
  • * No contraindications for periodontal surgery and not taking medications known to interfere with periodontal tissue health or healing; and no prior periodontal surgery on the involved sites
  • * Vaping, chewing tobacco or smoking \> 10 cigarettes per day
  • * Uncontrolled Diabetes Mellitus (HbA1c \> 7)
  • * Pregnancy and Lactation
  • * Diseases affecting connective tissue metabolism
  • * Long-term steroid use
  • * Recession defects associated with caries
  • * Teeth associated with pulpal pathology

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Case Western Reserve University,

Gian Pietro Schincaglia, DDS, PhD, PRINCIPAL_INVESTIGATOR, Case Western Reserve University

Study Record Dates

2025-07-30