RECRUITING

Passive Calf Stretching Therapy in Peripheral Artery Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to assess the effects of passive calf muscle stretching in patients diagnosed with peripheral artery disease (PAD). The main question it aims to answer are: 1. To determine if daily calf muscle stretching at home improves calf muscle and vascular health. 2. To determine if daily calf muscle stretching at home improves walking performance. Participants will use inflatable ankle splints for 30 minutes a day, 5 days a week for 4-weeks on both days and 4-weeks of no stretching.

Official Title

To Stretch, Not Strain: Impact of Passive Stretching on Calf Muscle and Gait Mechanics in PAD

Quick Facts

Study Start:2024-04-01
Study Completion:2026-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06041880

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Presence of PAD
  2. * Stable condition (PAD symptoms) for at least 3 months
  3. * Age 40-85
  4. * Men and women who are not pregnant or nursing
  1. * Ischemic leg pain at rest; critical limb ischemia (ulceration or gangrene)
  2. * Any condition other than PAD that limits the ability to walk
  3. * Major surgery or lower extremity revascularization surgery in the past 6 months
  4. * Myocardial infarction within past 6 months or unstable angina
  5. * Severe lung disease (on supplemental oxygen or frequently use rescue inhalers)
  6. * Participants with non-compressible vessels (ABI \> 1.40)
  7. * Habitual exercise (30 minutes of continuous activity on 3 or more days per week)
  8. * Current tobacco smoker or use of nicotine-containing products
  9. * Pregnant or nursing women
  10. * History or ankle reconstruction or surgery Recent history (\<1 year) of injuries to the ankle, Achilles tendon, or feet
  11. * History of rheumatoid arthritis or other degenerative joint disease
  12. * Major medical illness treatment during the prior 12 months
  13. * Uncontrolled hypertension
  14. * Uncontrolled diabetes
  15. * Inability to walk on a treadmill at a slow pace (1.0 mile/hour)

Contacts and Locations

Study Contact

David N Proctor, Ph.D.
CONTACT
814-571-5234
dnp3@psu.edu
Jocelyn M Delgado, B.S.
CONTACT
408-679-8390
jmd956@psu.edu

Study Locations (Sites)

Penn State University
University Park, Pennsylvania, 16802
United States

Collaborators and Investigators

Sponsor: Penn State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-04-01
Study Completion Date2026-07

Study Record Updates

Study Start Date2024-04-01
Study Completion Date2026-07

Terms related to this study

Keywords Provided by Researchers

  • Endothelial dysfunction

Additional Relevant MeSH Terms

  • Peripheral Artery Disease
  • Claudication, Intermittent