Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Description

The purpose of this study is to determine efficacy of guanfacine immediate release (GIR) for the treatment of hyperactivity/impulsivity and inattention in children 6-12 years of age with Down syndrome (DS) after 8 weeks of treatment.

Conditions

Hyperactivity in Children with Down Syndrome, Impulsivity in Children with Down Syndrome

Study Overview

Study Details

Study overview

The purpose of this study is to determine efficacy of guanfacine immediate release (GIR) for the treatment of hyperactivity/impulsivity and inattention in children 6-12 years of age with Down syndrome (DS) after 8 weeks of treatment.

Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Condition
Hyperactivity in Children with Down Syndrome
Intervention / Treatment

-

Contacts and Locations

Phoenix

Phoenix Childrens Hospital, Phoenix, Arizona, United States, 85016

New Haven

Yale University School of Medicine, New Haven, Connecticut, United States, 06250

Atlanta

Emory University, Atlanta, Georgia, United States, 30322

Chicago

Ann and Robert H. Lurie Hospital of Chicago, Chicago, Illinois, United States, 60611

Iowa City

University of Iowa, Iowa City, Iowa, United States, 52242

Baltimore

Kennedy Krieger Institute, Baltimore, Maryland, United States, 21205

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Lexington

Massachusetts General Hospital, Lexington, Massachusetts, United States, 02421

Charlotte

Atrium Health-Wake Forest School of Medicine, Charlotte, North Carolina, United States, 28204

Durham

Duke University Hospital, Durham, North Carolina, United States, 27705

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    6 Years to 12 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    Rachel G. Greenberg, MD, MB, MHS,

    Rachel Greenberg, PRINCIPAL_INVESTIGATOR, DCRI

    Study Record Dates

    2026-02