ACTIVE_NOT_RECRUITING

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)

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Conditions

Hyperactivity in Children With Down SyndromeImpulsivity in Children With Down Syndromehyperactivityimpulsivityinattention

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine efficacy of guanfacine immediate release (GIR) for the treatment of hyperactivity/impulsivity and inattention in children 6-12 years of age with Down syndrome (DS) after 8 weeks of treatment.

Official Title

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)

Quick Facts

Study Start:2024-12-09
Study Completion:2026-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT06042257

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:6 Years to 12 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Rachel Greenberg
PRINCIPAL_INVESTIGATOR
DCRI

Study Locations (Sites)

Phoenix Childrens Hospital
Phoenix, Arizona, 85016
United States
Yale University School of Medicine
New Haven, Connecticut, 06250
United States
Emory University
Atlanta, Georgia, 30322
United States
Ann and Robert H. Lurie Hospital of Chicago
Chicago, Illinois, 60611
United States
University of Iowa
Iowa City, Iowa, 52242
United States
Kennedy Krieger Institute
Baltimore, Maryland, 21205
United States
Boston Children's Hospital
Boston, Massachusetts, 02115
United States
Massachusetts General Hospital
Lexington, Massachusetts, 02421
United States
Atrium Health-Wake Forest School of Medicine
Charlotte, North Carolina, 28204
United States
Duke University Hospital
Durham, North Carolina, 27705
United States
Akron Children's Hospital
Akron, Ohio, 44308
United States
Cincinnati Children's Hospital
Cincinnati, Ohio, 45229
United States
Virginia Center for Children
Richmond, Virginia, 23220
United States
University of Washington
Seattle, Washington, 98195
United States
University of Wisconsin Madison
Madison, Wisconsin, 53792
United States

Collaborators and Investigators

Sponsor: Rachel G. Greenberg, MD, MB, MHS

  • Rachel Greenberg, PRINCIPAL_INVESTIGATOR, DCRI

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-09
Study Completion Date2026-07

Study Record Updates

Study Start Date2024-12-09
Study Completion Date2026-07

Terms related to this study

Keywords Provided by Researchers

  • hyperactivity
  • impulsivity
  • inattention

Additional Relevant MeSH Terms

  • Hyperactivity in Children With Down Syndrome
  • Impulsivity in Children With Down Syndrome