Vision Loss Impact on Navigation in Virtual Reality

Description

The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).

Conditions

Stroke, Ischemic, Quadrantanopia, Hemianopsia, Homonymous, Hemianopia, Homonymous, Hemianopia, Hemianopsia, Occipital Lobe Infarct, Visual Field Defect, Peripheral, Vision Loss Partial, Quadrantanopsia, Stroke Hemorrhagic

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Study Details

Study overview

The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).

The Impact of Vision Loss on Naturalistic Behavior and Navigation in Virtual Reality

Vision Loss Impact on Navigation in Virtual Reality

Condition
Stroke, Ischemic
Intervention / Treatment

-

Contacts and Locations

Rochester

University of Rochester, Rochester, New York, United States, 14642

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Residents of the United States or Canada
  • * Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and/or CT scans)
  • * Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.
  • * Willing, able, and competent to provide their own informed consent
  • * Cognitively able, responsible to understand written and oral instructions in English
  • * Emmetropic or else wear corrective contact lenses inside the virtual reality headset
  • * Those who have never driven or earned a drivers' license
  • * Past or present ocular disease interfering with visual acuity
  • * Best corrected visual acuity (BCVA) worse than 20/40 in either eye
  • * Sustained damage to the dorsal lateral geniculate nucleus
  • * Presence of diffuse, whole-brain degenerative processes
  • * Presence of brain damage deemed by study staff to potentially interfere with outcome measures
  • * History of traumatic brain injury
  • * Documented history of drug/alcohol abuse
  • * Diagnosis of cognitive or seizure disorders
  • * Diagnosis of one-sided attentional neglect

Ages Eligible for Study

21 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Rochester,

Study Record Dates

2026-10