Spatial-Motor Stroke-Rehab Study

Description

The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.

Conditions

Spatial Neglect, Stroke

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Study Overview

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Study Details

Study overview

The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.

Novel Spatial-Motor Approaches to Improve Spatial Neglect and Walking Deficits Post-Stroke

Spatial-Motor Stroke-Rehab Study

Condition
Spatial Neglect
Intervention / Treatment

-

Contacts and Locations

Atlanta

Emory Rehabilitation Hospital, Atlanta, Georgia, United States, 30322

Atlanta

Emory University Hospital (EUH), Atlanta, Georgia, United States, 30322

Atlanta

Executive Park, Atlanta, Georgia, United States, 30329

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18-30 years
  • * Able-Bodied (healthy without any physical disability or neurological disorder)
  • * 45-90 years
  • * Able-Bodied (healthy without any physical disability or neurological disorder)
  • * \>3 months following stroke.
  • * Presence of Aiming SN
  • * Ability to walk \>10m with or without assistive devices.
  • * Unilateral left-sided hemiparesis with gross arm strength of ≤ grade 4/5 on the Medical Research Council Scale
  • * Ability to follow 3-stage commands and provide informed consent.
  • * History or evidence of orthopedic or physical disability
  • * History or evidence of neurological pathology
  • * Pregnancy (female)
  • * Uncontrolled hypertension
  • * Cardiac pacemaker or other implanted electronic system
  • * Presence of skin conditions preventing electrical stimulation setup
  • * Impaired sensation in the left upper limb.
  • * Bruises or cuts at the stimulation electrode placement site
  • * Concurrent enrollment in rehabilitation or another investigational study.
  • * History or evidence of orthopedic or physical disability interfering with study procedures
  • * History or evidence of neurological pathology or disorder
  • * Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures
  • * Contraindications to TMS such as metal implants, medications that can increase cortical excitability, unexplained dizziness in the past 6 months
  • * History of multiple strokes or brainstem strokes
  • * Cerebellar disorders
  • * Impaired sensation in the left upper limb.
  • * History of other neurological disorders
  • * Uncontrolled hypertension
  • * Cardiac pacemaker or other implanted electronic system
  • * Pregnancy (female)
  • * Presence of skin condition
  • * Bruises at the electrode placement site
  • * Concurrent enrollment in rehabilitation or another investigational study
  • * Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) or other medical conditions that can interfere with study procedures
  • * Contraindications to TMS such as metal implants in the brain, medications that will increase cortical excitability, etc.

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Emory University,

Trisha Kesar, PT, PhD, PRINCIPAL_INVESTIGATOR, Emory University

Fisayo Aloba, PT, DPT, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

2025-12-31