Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance

Description

In this project we want to assess impact of dietary fructose as a simple sugar intolerance on abdominal pain and compare a low FODMAP diet versus an added sugar elimination diet effectiveness on symptoms but also impact on microbiome and its metabolome.

Conditions

Carbohydrate Intolerance

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Study Overview

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Study Details

Study overview

In this project we want to assess impact of dietary fructose as a simple sugar intolerance on abdominal pain and compare a low FODMAP diet versus an added sugar elimination diet effectiveness on symptoms but also impact on microbiome and its metabolome.

Clinical Comparison of the Impact of Two Dietary Interventions on Abdominal Pain and Intestinal Microbiome Caused by Simple Carbohydrate Intolerance.

Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance

Condition
Carbohydrate Intolerance
Intervention / Treatment

-

Contacts and Locations

Springfield

Oregon Health and Science University, Springfield, Oregon, United States, 97477

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age: 5- 18-year-old
  • * BMI: within normal range for age
  • * Positive fructose breath test performed as part of diagnostic work up for abdominal pain
  • * Willingness to consume low FODMAP and Limited Added sugar diet trial and collect required samples
  • * Age: not within range
  • * BMI: not within range
  • * Negative fructose breath test
  • * Any known or suspected intestinal disorder including but not limited to IBD, IBS, celiac disease, Crohn's Disease, food sensitivities, food allergies, significant by-choice food restrictions
  • * Hormonal disorders
  • * Use of chronic medications including contraceptives (both oral and subcutaneous), non-hormone secreting IUD- accepted
  • * Use of oral or IV antibiotics in the last three months
  • * Daily probiotic use (pill form)
  • * Daily multi-vitamin except vitamin D supplements

Ages Eligible for Study

5 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

Anna Hunter, MD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2026-02