Microbes and Respiratory Illnesses

Description

This study is called the Microbes and Respiratory Illnesses (MARI) Study. Children growing up on farms are exposed to many types of microbes that could be beneficial. It is thought that increased exposure to certain types of microbes early in life helps to develop a healthy immune system and reduce the risk for severe common cold illnesses, breathing problems, and allergies.

Conditions

Virus, Asthma

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Study Overview

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Study Details

Study overview

This study is called the Microbes and Respiratory Illnesses (MARI) Study. Children growing up on farms are exposed to many types of microbes that could be beneficial. It is thought that increased exposure to certain types of microbes early in life helps to develop a healthy immune system and reduce the risk for severe common cold illnesses, breathing problems, and allergies.

Microbes and Respiratory Illnesses, The MARI Study

Microbes and Respiratory Illnesses

Condition
Virus
Intervention / Treatment

-

Contacts and Locations

Madison

University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States, 53792

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Participant and/or parent guardian must be able to understand and provide informed consent
  • 2. Children ages 4-12 years of age
  • 3. Cohort 1: Family is self-identified as Plain community member
  • 4. Cohort 2: Madison-area children with parental report of doctor-diagnosed asthma
  • 5. Cohort 3: Madison-area children with no history of asthma by parental report
  • 6. Cohort 4: Madison-area children who have an active respiratory illness
  • 1. Inability or unwillingness of a participant to give written informed consent or comply with study protocol
  • 2. Chronic sinusitis (frequent sinus infections)
  • 3. Plans to move out of the area before completing the study
  • 4. Past or current medical problems or findings from physical examination or laboratory testing that are not listed above, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study
  • 5. Enrolled family member

Ages Eligible for Study

4 Years to 12 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Wisconsin, Madison,

James Gern, MD, PRINCIPAL_INVESTIGATOR, UW Madison

Study Record Dates

2027-12