An Adjunct Test Distinguishing Bacterial From Viral Etiology Improves Resource Utilization and Efficiency in the ED.

Description

The purpose of this study is to evaluate overall changes in patient management and longer-term resource utilization between control and test arms, including (but not limited to) additional work-up (including other diagnostic tests and consults), antimicrobial treatments, disposition decisions and hospital length of stay (LOS)

Conditions

Respiratory Tract Infections

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this study is to evaluate overall changes in patient management and longer-term resource utilization between control and test arms, including (but not limited to) additional work-up (including other diagnostic tests and consults), antimicrobial treatments, disposition decisions and hospital length of stay (LOS)

Does an Adjunct Diagnostic Test That Can Discriminate Bacterial From Viral Etiology Early in the Management of Respiratory Infections Improve Management Accuracy and Quality in the Acute Care Setting?

An Adjunct Test Distinguishing Bacterial From Viral Etiology Improves Resource Utilization and Efficiency in the ED.

Condition
Respiratory Tract Infections
Intervention / Treatment

-

Contacts and Locations

Houston

The University of Texas Health Science Center at Houston, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Current disease duration ≤ 7 days
  • * Temperature ≥ 37.8°C (100°F) or tactile fever, noted at least once within the last 7 days
  • * Clinical suspicion of bacterial or viral respiratory tract infection (RTI)
  • * Blood tests are being ordered
  • * Systemic antibiotics taken up to 48 hours prior to presentation
  • * Outpatient steroids taken within 48 hours prior to presentation
  • * Suspicion and/or confirmed diagnosis of infectious gastroenteritis/colitis
  • * Inflammatory disease
  • * Congenital immune deficiency (CID)
  • * A proven or suspected infection on the presentation with Mycobacterial ,parasitic or fungal (e.g., Candida, Histoplasma, Aspergillus) pathogen
  • * Human immunodeficiency virus(HIV), Hepatitis B Virus (HBV), or Hepatitis C Virus (HCV) infection (self-declared or known from medical records)
  • * Major trauma and/or burns in the last 7 days
  • * Major surgery in the last 7 days
  • * Pregnancy - Self reported or medically confirmed
  • * Active malignancy - Cancer diagnosed within the previous six months, recurrent, regionally advanced, or metastatic cancer, cancer for which treatment had been administered within six months, or hematological cancer that is not in complete remission.
  • * Current treatment with immune-suppressive or immune-modulating therapies, at some point in the past 10 days
  • * Hemodynamically unstable (require life-saving interventions such as vasopressors)
  • * Patients transferred from another facility who already have a differentiated respiratory illness (known diagnosis e.g., culture positive results)
  • * Consider unsuitable for the study by the study team

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The University of Texas Health Science Center, Houston,

David Robinson, MD,MS,MMM, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center, Houston

Study Record Dates

2024-12-30