RECRUITING

Non Inferiority Trial Investigating Surfactants Administered Via MIST

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome. Infants who are on NCPAP and FiO2 ≥0.30 will randomized to curosurf or infasurf via MIST. Exclusion criteria Infants will be excluded if there is a congenital anomaly or an alternative cause for respiratory distress. Babies who require emergent intubation will not be enrolled in the interventions. Parental Consent will be obtained prior to randomization.

Official Title

Non Inferiority Trial Investigating Surfactants Administered Via MIST

Quick Facts

Study Start:2024-01-01
Study Completion:2027-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06074380

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 48 Hours
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome confirmed by a chest x-ray on nasal continuous positive airway pressure (NCPAP) and FiO2 ≥0.30
  1. * Infants will be excluded if there is a congenital anomaly or an alternative cause for respiratory distress.
  2. * Infants who require emergent intubation will not be enrolled in the interventions.

Contacts and Locations

Study Contact

Matthew Derrick
CONTACT
18475702920
mderrick@northshore.org

Study Locations (Sites)

Northshore University Healthsystem
Evanston, Illinois, 60201
United States

Collaborators and Investigators

Sponsor: NorthShore University HealthSystem

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-01
Study Completion Date2027-12-01

Study Record Updates

Study Start Date2024-01-01
Study Completion Date2027-12-01

Terms related to this study

Keywords Provided by Researchers

  • Pulmonary Surfactant
  • CPAP
  • Neonate

Additional Relevant MeSH Terms

  • Respiratory Distress Syndrome