Stimulation for Bowel Emptying

Description

The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which means that stools take longer than normal to pass through the colon. This slowed movement may result in chronic constipation and difficulty emptying the bowels. Individuals typically (without or without caregiver assistance) insert a gloved finger into the rectum and gently stretch it to improve colonic motility for a brief period to empty the bowels. The investigators hypothesize that electrically stimulating the rectum, instead of mechanically stretching it, will produce the same beneficial effect of improving colonic motility. Therefore, this study will compare the two methods. If electrical stimulation effectively improves colonic motility, then the investigator shall develop the approach as a therapeutic intervention in future studies.

Conditions

Neurogenic Bowel Dysfunction

Study Overview

Study Details

Study overview

The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which means that stools take longer than normal to pass through the colon. This slowed movement may result in chronic constipation and difficulty emptying the bowels. Individuals typically (without or without caregiver assistance) insert a gloved finger into the rectum and gently stretch it to improve colonic motility for a brief period to empty the bowels. The investigators hypothesize that electrically stimulating the rectum, instead of mechanically stretching it, will produce the same beneficial effect of improving colonic motility. Therefore, this study will compare the two methods. If electrical stimulation effectively improves colonic motility, then the investigator shall develop the approach as a therapeutic intervention in future studies.

Electrical Rectal Stimulation to Promote Bowel Emptying After Spinal Cord Injury

Stimulation for Bowel Emptying

Condition
Neurogenic Bowel Dysfunction
Intervention / Treatment

-

Contacts and Locations

Syracuse

Syracuse VA Medical Center, Syracuse, NY, Syracuse, New York, United States, 13210-2716

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Suprasacral spinal cord injury
  • * Diagnosed neurogenic bowel dysfunction and using digital rectal stimulation
  • * Bowel routine requires at least 30 minutes or at least 3 cycles of digital rectal stimulation
  • * Neurologically stable
  • * At least 18 years old
  • * At least 12 months post neurological injury or disease diagnosis
  • * Active sepsis
  • * Open pressure sores on or around pelvis
  • * Significant colon trauma or colostomy
  • * Crohn's disease
  • * Colonic obstruction or gastrointestinal surgery within last 3 months
  • * Significant history of autonomic dysreflexia

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

VA Office of Research and Development,

Cesar Colasante-Garrido, MD, PRINCIPAL_INVESTIGATOR, Syracuse VA Medical Center, Syracuse, NY

Study Record Dates

2026-12-31